16775-57-8Relevant academic research and scientific papers
Proton-Ionizable Crown Compounds. 8. Synthesis and Structural Studies of Macrocyclic Polyether Ligands Containing a 4-Thiopyridone Subcyclic Unit
Brandshaw, Jerald S.,Huszthy, Peter,Koyama, Hiroyuki,Wood, Steven G.,Strobel, Scott A.,et al.
, p. 1837 - 1843 (2007/10/02)
Three new proton-ionizable macrocyclic polyether ligands containing the 4-pyridone subcyclic group have been prepared.Two of these ligands contain lipophilic n-octyl substituents, the other ligand contains a phenyl substituent.The 15-crown-5 ligand containing both a 4-pyridone subcyclic unit and n-octyl substituent selectively transported lithium cations in water-methylene chloride-water bulk liquid membrane system.Five crown compounds containing the 4-pyridone subcyclic unit were converted to the 4-thiopyridono-crown compounds when treated with Lawesson's Reagent.The crystal structure of 4-thiopyridono-18-crown-6 shows a carbon-sulphur double bond and a molecule of water hydrogen bonded inside the macrocycle cavity.
