167777-14-2

Upstream product

• 34370-91-7 3-O-benzyl-1,2-O-isopropylidene-α-D-xylofuranose 
• 106-95-6 allyl bromide 
• 42926-89-6 1,2-O-isopropylidene-3-O-benzyl-α-D-glucofuranose 
• 23558-05-6 3-O-benzyl-1,2-O-isopropylidene-1,5-D-xylo-dialdofuranose 

Downstream Products

• 1391597-15-1 (2S,3S,4R,5R)-2-allyl-5-(allyloxymethyl)-4-(benzyloxy)tetrahydrofuran-3-ol 
• 1391597-17-3 9-(((2R,3S,3aR,8aS)-3-(benzyloxy)-2,3,3a,5,8,8a-hexahydrofuro[3,2-b]oxepin-2-yl)methyl)-N,N-dimethyl-9H-purin-6-amine 
• 1391597-16-2 9-(((2R,3S,4R,5S)-5-allyl-4-(allyloxy)-3-(benzyloxy)tetrahydrofuran-2-yl)methyl)-9H-purin-6-amine 
• 1391597-31-1 C₁₉H₂₃F₃O₆S 

Relevant academic research and scientific papers

Allyloxy and propargyloxy group migration: Role of remote group participation in the synthesis of 5-C-nucleosides and other sugar derivatives

In 1-deoxy-xylofuranose derivatives possessing a good leaving group at 2-C, participation of allyloxy and propargyloxy substituents at 5-C results in loss of the 2-C substituent and attack of various nucleophiles at 5-C of the oxonium intermediate. Such p

Synthesis of unnatural enantiomer of nectrisine and its biological activity

ent-Nectrisine (2), the unnatural enantiomer of nectrisine (1), a potent α-glucosidase inhibitor, was synthesized from D-glucose derivative. Biological assay showed that 2 had no significant bioactivity.

Asymmetric induction in the epoxidation of 3- and 5-O-allyl glycofuranoses with mCPBA

Diastereoselective epoxidation of 3- and 5-O-allyl-1,2-O-isopropylidene-α-D-glycofuranoses (2, 6, 10, and 14) with mCPBA has been reported. Asymmetric induction in the resulting products varies (40 to 100%) with the position and configuration of allyloxy