16782-39-1

Basic information

• Product Name: tricyclo[3.3.1.1~3,7~]dec-1-ylhydrazine
• Synonyms: 1-(1-Adamantyl)hydrazine; 1-Hydrazinoadamantane
• CAS NO: 16782-39-1
• Molecular Formula: C₁₀H₁₈N₂
• Molecular Weight: 166.2633
• Mol File: 16782-39-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 284°C at 760 mmHg
• Flash Point: 145.7°C
• Density: 1.09g/cm³
• Vapor Pressure: 0.00306mmHg at 25°C
• Refractive Index: 1.566
• CAS DataBase Reference: tricyclo[3.3.1.1~3,7~]dec-1-ylhydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: tricyclo[3.3.1.1~3,7~]dec-1-ylhydrazine(16782-39-1)
• EPA Substance Registry System: tricyclo[3.3.1.1~3,7~]dec-1-ylhydrazine(16782-39-1)

Safety Data

• Hazardous Substances Data: 16782-39-1(Hazardous Substances Data)

Upstream product

• 768-90-1 1-Adamantyl bromide 

Downstream Products

• 69625-62-3 1-(1-adamantyl)-1,2,4-triazole 
• 92234-54-3 1-((3s,5s,7s)-adamantan-1-yl)-1H-pyrazole 

Relevant articles and documents

A Catalyst-Free, Temperature-Driven One-Pot Synthesis of 1-Adamantylhydrazine Hydrochloride

1-Adamantylhydrazine can be a versatile intermediate for many biologically active compounds as adamantyl possesses a wide spectrum of medicinal properties. Described here is a detailed one-pot synthesis of 1-adamantylhydrazine, carried out on a milligram to gram scale, that steadily delivers a highly stable product used to carry out the synthesis of 1-(adamantan-1-yl)-1 H -pyrazol-3-amine for bacterial studies. The reaction employs inexpensive, catalyst free, readily available starting materials. In the synthesis of 1-(adamantan-1-yl)-1 H -pyrazol-3-amine, the use of a continuous extraction method allows for complete extraction of the target product into the organic layer and increases the overall percentage yield.