167824-48-8 Usage
General Description
The chemical "(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1-(5-hydroxypentyl)-3-(naphthalen-2-ylmethyl)-1,3-diazepan-2-one" is a complex compound with a diazepane ring structure. It contains two benzyl groups, two hydroxyl groups, a hydroxypentyl group, and a naphthalen-2-ylmethyl group. The compound also has a chiral center, with the (4R,5S,6S,7R) configuration. This chemical likely has applications in medicinal chemistry and may be used in the development of pharmaceuticals or as a research tool in biochemistry and pharmacology. Its specific properties and potential uses would require further research and investigation.
Check Digit Verification of cas no
The CAS Registry Mumber 167824-48-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,8,2 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 167824-48:
(8*1)+(7*6)+(6*7)+(5*8)+(4*2)+(3*4)+(2*4)+(1*8)=168
168 % 10 = 8
So 167824-48-8 is a valid CAS Registry Number.
167824-48-8Relevant articles and documents
Functionalized aliphatic P2/P2' analogs of HIV-1 protease inhibitor DMP323
Smallheer, Joanne M.,McHugh, Robert J.,Chang, Chong-Hwan,Kaltenbach III, Robert F.,Worley, Tabitha V.,Klabe, Ronald M.,Bacheler, Lee T.,Rayner, Marlene M.,Erickson-Viitanen, Susan,Seitz, Steven P.
, p. 1365 - 1370 (2007/10/03)
A series of analogs of HIV protease inhibitor DMP323 containing functionalized aliphatic P2/P2' groups was prepared and evaluated for HIV protease inhibition and antiviral activity in a cell-based assay. Asymmetric compounds with a 5-hydroxypentyl substituent at P2 and a benzylic substituent at P2' showed increased potency over the corresponding symmetrically substituted analogs.