167886-83-1Relevant academic research and scientific papers
METHODS OF USING AND COMPOSITIONS COMPRISING (+)-3-(3,4-DIMETHOXY-PHENYL)-3-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPIONAMIDE
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Page/Page column 32-33; 38, (2008/06/13)
Enantiomerically pure (+)-3 -(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide, and prodrugs, metabolites, polymorphs, salts, solvates (e.g., hydrates), and clathrates thereof are discussed. Methods of treating and/or preventing vari
Asymmetric synthesis of quinolizidine alkaloids (-)-lasubine I, (-)- lasubine II and (+)-subcosine II
Chalard, Pierre,Remuson, Roland,Gelas-Mialhe, Yvonne,Gramain, Jean-Claude
, p. 4361 - 4368 (2007/10/03)
The enantioselective synthesis of (-)-lasubine I 1 and the first asymmetric synthesis of (-)-lasubine II 2 and (+)-subcosine II 3 is described. The key step is the intramolecular cyclization of N-acyliminium ion 4 which is derived from (S)-aminoester 6.
