167947-08-2Relevant articles and documents
Anesthetic activity of novel water-soluble 2β-morpholinyl steroids and their modulatory effects at GABA(A) receptors
Anderson, Alison,Boyd, Andrew C.,Byford, Alan,Campbell, Alexander C.,Gemmell, David K.,Hamilton, Niall M.,Hill, David R.,Hill-Venning, Claire,Lambert, Jeremy J.,Maidment, Maurice S.,May, Valerie,Marshall, Richard J.,Peters, John A.,Rees, David C.,Stevenson, Donald,Sundaram, Hardy
, p. 1668 - 1681 (2007/10/03)
(3α,5α)-3-Hydroxypregnan-20-ones and (3α,5α)-3-hydroxypregnane- 11,20-diones bearing a 2β-morpholinyl substituent were synthesized, and the utility of these steroids as anesthetic agents was evaluated through determination of their potency and duration of
Substituted 2β-morpholino-androstane derivatives
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, (2008/06/13)
The invention is related to substituted 2β-morpholino-androstane derivatives, bonded at their 2β-position to the nitrogen of a group of formula I STR1 wherein R represents one to four substituents, each one independently selected from (1-4C) alkyl, phenyl