167979-41-1Relevant academic research and scientific papers
Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites
Komoriya, Satoshi,Kanaya, Naoaki,Nagahara, Takayasu,Yokoyama, Asako,Inamura, Kazue,Yokoyama, Yukio,Katakura, Shin-Ichi,Hara, Tsuyoshi
, p. 2099 - 2114 (2007/10/03)
Since factor Xa (fXa) plays a pivotal role in the blood coagulation cascade, inhibition of fXa is thought to be an effective treatment for a variety of thrombotic events. (2S)-2-[4-[[(3S)-1-Acetimidoyl-3-pyrrolidinyl]oxy]phenyl] -3-(7-amidino-2-naphthyl)p
