167993-16-0

Usage

Molecular Weight

264.22 g/mol

Structure

A furobenzimidazole backbone with dione functional groups

Heterocyclic compound

Consists of a benzimidazole ring with a furan ring fused to it

Biological Activity

Known for its diverse biological activities, including potential use in pharmaceuticals and medicinal chemistry

Unique Structure

The combination of furobenzimidazole backbone and dione functional groups makes it a valuable molecule for further research and development in drug discovery and design.

Upstream product

• 10351-75-4 1H-benzimidazole-5,6-dicarboxylic acid 
• 108-24-7 acetic anhydride 
• 167993-10-4 indole-5,6-dicarboxylic acid anhydride 
• 582-60-5 5,6-dimethyl-1H-benzo[d]imida-zole 

Downstream Products

• 494847-59-5 5-[[[[3,5-bis(benzyloxycarbonyl)phenyl]amino]carbonyl]-[2-(1,2,3,4,5,6,7,8-octahydro-3-benzazecino)carbonyl]]-6-(carboxylic acid)benzimidasole 
• 1027934-40-2 5-[(S)-2-({6-[(Adamantan-1-ylmethyl)-carbamoyl]-1H-benzoimidazole-5-carbonyl}-amino)-3-(4-hydroxy-phenyl)-propionylamino]-isophthalic acid dibenzyl ester 
• 1026318-99-9 5-[(S)-2-({6-[(Adamantan-1-ylmethyl)-carbamoyl]-1H-benzoimidazole-5-carbonyl}-amino)-3-(2-fluoro-phenyl)-propionylamino]-isophthalic acid dibenzyl ester 
• 167992-94-1 2,2-Dimethyl-propionic acid 5-{3-[(S)-2-({6-[(adamantan-1-ylmethyl)-carbamoyl]-1H-benzoimidazole-5-carbonyl}-amino)-3-phenyl-propionylamino]-5-[1-(2,2-dimethyl-propionyloxymethyl)-1H-tetrazol-5-yl]-phenyl}-tetrazol-1-ylmethyl ester 
• 167992-92-9 5-(1S-(3-benzyloxycarbonylphenylaminocarbonyl)-2-phenylethylaminocarbonyl)-benzimidazole-6-carboxylic acid 
• 192134-00-2 5-[[[[3,5-bis(benzyloxycarbonyl)phenyl]amino]carbonyl]-[2-(2,3,4,5,6,7-hexahydro-1H-3-benzazonino)carbonyl]]-6-[[(1-adamantanemethyl)amino]carbonyl]benzimidasole 
• 192133-99-6 5-[[[[3,5-bis(benzyloxycarbonyl)phenyl]amino]carbonyl]-[2-(1,2,3,4,5,6-hexahydro-3-benzazocino)carbonyl]]-6-[[(1-adamantanemethyl)amino]carbonyl]benzimidasole 
• 192133-98-5 5-[[[[3,5-bis(benzyloxycarbonyl)phenyl]amino]carbonyl]-[2-(2,3,4,5-tetrahydro-1H-3-benzazepino)carbonyl]]-6-[[(1-adamantanemethyl)amino]carbonyl]benzimidasole 
• 192133-97-4 5-[[[[3,5-bis(benzyloxycarbonyl)phenyl]amino]carbonyl]-[3-(1,2,3,4-tetrahydroisoquinolino)carbonyl]]-6-[[(1-adamantanemethyl)amino]carbonyl]benzimidasole 

Relevant academic research and scientific papers

Size-expanded analogues of dG and dC: Synthesis and pairing properties in DNA

(Chemical Equation Presented) We describe the completion of the set of four benzo-fused expanded DNA (xDNA) nucleoside analogues. We previously reported the development of benzo-fused analogues of dA and dT and their inclusion in an exceptionally stable n

GASTIN AND CCK RECEPTOR LIGANDS

Compounds of formula (Ia), (Ib), or (Ic), wherein A represents a group having two fused rings, or a group of formula (Id), R 1 (m) represents up to 6 substituents, K represents--O--,--S--,--CH 2--,--N(R 2)--or--N(COR 2)--, in which R 2 is H or C 1 to C 3 alkyl, W is a carbonyl, sulfonyl or sulfinyl group, provided that at least one of W and X contains carbonyl, Y and Z are as given in the description, and their pharmaceutically acceptable salts are ligands at CCK and/or gastrin receptors. STR1

Non-peptide cholecystokinin-B/gastrin receptor antagonists based on bicyclic, heteroaromatic skeletons

A series of potent and selective cholecystokinin-B/gastrin receptor antagonists based on the dibenzobicyclo[2.2.2]octane (BCO) skeleton which have recently been described were found to show species-dependent behavior when examined in rat and dog models. W