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Boc-2,4-Difluoro-D-Phenylalanine, also known as Fmoc-D-Phe(2,4-F2)-OH, is a modified amino acid that is widely used in peptide synthesis. It is a derivative of the essential amino acid phenylalanine, distinguished by the presence of two fluorine atoms, which makes it fluorinated. The Boc-protecting group in its structure helps prevent unwanted side reactions during the synthesis process. Boc-2,4-Difluoro-D-Phenylalanine is highly specific and is primarily purchased for research purposes, as it is crucial for the production of peptide sequences that are essential in various scientific and pharmaceutical studies.

167993-24-0

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167993-24-0 Usage

Uses

Used in Pharmaceutical Industry:
Boc-2,4-Difluoro-D-Phenylalanine is used as a building block for the synthesis of peptides and proteins for pharmaceutical applications. The incorporation of this fluorinated amino acid into peptide sequences can lead to the development of novel drugs with improved pharmacokinetic properties, such as increased stability, enhanced bioavailability, and better target specificity.
Used in Research Applications:
In the field of research, Boc-2,4-Difluoro-D-Phenylalanine is used as a key component in the synthesis of various peptide sequences. It is particularly valuable in studies focused on understanding the structure-function relationships of peptides and proteins, as well as in the development of new therapeutic strategies based on peptide-based drugs.
Used in Peptide Synthesis:
Boc-2,4-Difluoro-D-Phenylalanine is used as a protected amino acid in the stepwise synthesis of peptides. The Boc-protecting group allows for the selective deprotection and coupling of amino acids during the synthesis process, ensuring the formation of the desired peptide sequence with minimal side reactions and impurities.
Used in Drug Discovery:
Boc-2,4-Difluoro-D-Phenylalanine is used as a potential candidate in drug discovery, where its unique properties, such as the presence of fluorine atoms, can contribute to the development of new drugs with improved efficacy and safety profiles. The incorporation of this amino acid into peptide-based drug candidates can lead to the identification of novel therapeutic agents with enhanced pharmacological properties.

Check Digit Verification of cas no

The CAS Registry Mumber 167993-24-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,9,9 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 167993-24:
(8*1)+(7*6)+(6*7)+(5*9)+(4*9)+(3*3)+(2*2)+(1*4)=190
190 % 10 = 0
So 167993-24-0 is a valid CAS Registry Number.

167993-24-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-3-(2,4-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

1.2 Other means of identification

Product number -
Other names BOC-D-PHE(2,4-F2)-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:167993-24-0 SDS

167993-24-0Downstream Products

167993-24-0Relevant academic research and scientific papers

Synthesis of a complete set of L-difluorophenylalanines, L-(F2)Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor

Fujita, Tsugumi,Nose, Takeru,Matsushima, Ayami,Okada, Kazushi,Asai, Daisuke,Yamauchi, Yasuko,Shirasu, Naoto,Honda, Takeshi,Shigehiro, Daiki,Shimohigashi, Yasuyuki

, p. 923 - 927 (2007/10/03)

A complete set of difluorophenylalanines in the L-configuration [L- (F2)Phe] (namely, L-(2,3-F2)Phe, L-(2,4-F2)Phe, L-(2,5-F2)Phe, L-(2,6- F2)Phe, L-(3,4-F2)Phe, L-(3,5-F2)Phe) w

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