16801-62-0

Usage

Uses

Used in Pharmaceutical Industry:
N-CBZ-4-HYDROXYCYCLOHEXANE is used as a key intermediate in the synthesis of various drugs and bioactive compounds. Its presence in the molecular structure allows for the development of new pharmaceuticals with potential therapeutic applications.
Used in Organic Synthesis:
N-CBZ-4-HYDROXYCYCLOHEXANE is utilized as a building block in organic synthesis, contributing to the creation of a wide range of chemical compounds. Its versatile reactivity makes it a valuable component in the development of new molecules with specific properties and functions.
Used in Research and Development:
Due to its unique structure and properties, N-CBZ-4-HYDROXYCYCLOHEXANE is employed in research and development for the exploration of new compounds and their potential applications. It serves as a starting material for the synthesis of novel molecules with potential uses in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Agrochemical Industry:
N-CBZ-4-HYDROXYCYCLOHEXANE is used as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness and selectivity, leading to improved agricultural practices and crop protection.

InChI:InChI=1/C14H19NO3/c16-13-8-6-12(7-9-13)15-14(17)18-10-11-4-2-1-3-5-11/h1-5,12-13,16H,6-10H2,(H,15,17)

Upstream product

• 6850-65-3 p-hydroxycyclohexylamine 
• 501-53-1 benzyl chloroformate 
• 7107-58-6 benzyl N-cyclohexylcarbamate 
• 27489-62-9 trans-4-aminocyclohexan-1-ol 
• 27489-62-9 trans-4-hydroxycyclohexylamine 

Downstream Products

• 16801-63-1 benzyl N-(4-oxocyclohexyl)carbamate 
• 121936-51-4 4-<<(1-dimethylethyl)dimethylsilyl>oxy>cyclohexanamine 
• 121936-52-5 (1,1-dimethylethyl)dimethyl<(4-nitrocyclohexyl)oxy>silane 
• 121936-54-7 phenylmethyl <4-hydroxyimino)cyclohexyl>carbamate 
• 121936-55-8 phenylmethyl (4-chloro-4-nitrosocyclohexyl)carbamate 
• 121936-57-0 phenylmethyl (4-nitrocyclohexyl)carbamate 
• 121936-56-9 phenylmethyl (4-chloro-4-nitrocyclohexyl)carbamate 
• 65283-38-7 trans-4-nitrocyclohexanol 
• 130686-62-3 cis-4-nitrocyclohexanol 
• 130686-64-5 trans-4-nitrocyclohexanamine monohydrobromide 
• 130686-63-4 cis-4-nitrocyclohexanamine monohydrobromide 
• 1192764-38-7 γ-(carbamic acid benzyl ester)-ε-caprolactone 
• 1445875-29-5 C₂₃H₃₉NO₃Si 
• 121936-50-3 phenylmethyl <4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>cyclohexyl>carbamate 

Relevant academic research and scientific papers

IRAK INHIBITORS AND USES THEREOF

The present invention provides quinazoline and quinoline compounds, compositions thereof, and methods of using the same. Also disclosed is the activity of such compounds as inhibitors of IRAK enzymes.

FLT3 INHIBITORS AND USES THEREOF

The present invention provides methods of using compounds of formula I: or compositions thereof for the inhibition of FLT3, and the treatment of FLT3-mediated disorders.

Synthesis and solution properties of pH responsive methoxy poly(ethylene glycol)-b-poly(γ-amino-ε-caprolactone)

A series of water-soluble and cationic methoxy poly(ethylene glycol)-b-poly(γ-amino-ε-caprolactone) (mPEG-b-PACL) has been synthesized via ring opening polymerization of γ-(carbamic acid benzyl ester)-ε-caprolactone (γCABεCL) using mPEG as a macroinitiato

Serotonin derivatives as a new class of non-ATP-competitive receptor tyrosine kinase inhibitors

The discovery of new templates and their subsequent elaboration to clinically useful receptor tyrosine kinase (RTK) inhibitors continues to be an important issue. RTKs are a class of enzymes responsible for the activation of different cellular signal transduction cascades. The majority of the known small molecules RTK inhibitors are ATP-competitive and they are multiple targeted inhibitors. We describe here serotonin derivatives as a new class of multiple targeted RTK inhibitors. In contrast to most other RTK inhibitors they act via a non-ATP-competitive (allosteric) mechanism. Furthermore, they are able to inhibit the proliferation of HUVE cells, fibroblasts and two cancer cell lines.

BIFUNCTIONAL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional hetercyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents.

2,3-oxidosqualene-lanosterol cyclase inhibitors

The present invention relates to aminocyclohexanol derivatives useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones, tumors and/or hyperproliferative disorders, and treatment and/or prophylaxis of impaired glucose tolerance and diabetes.

Phenol compound having antioxidative activity and the process for preparing the same

Disclosed are a phenol compound represented by the formula (1): STR1 wherein R0 represents H, alkyl or alkyloxy; R1 represents alkyl; R2 represents alkyl or alkyloxy; OR3 represents OH; R4 represents H, lower alkyl or acyl, each of the above substituents may be substituted; W represents O, S or NR7 ; where R7 represents H, alkyl, aryl, OH or alkyloxy, a group of the formula (2): STR2 represents an amino which may be mono- or di-substituted or heterocyclic group containing N atom, or a pharmaceutically acceptable salt thereof, and a process for preparing the same.

Syntheses of the Saturated Analogues of 4-Nitrophenol and 4-Nitroaniline

Two syntheses for 4-nitrocyclohexanol and 4-nitrocyclohexanamine are presented.Both conveniently start from commercially available 4-aminocyclohexanol.