16803-75-1

Basic information

• Product Name: BROMAMPHENICOL
• Synonyms: Acetamide, 2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
• CAS NO: 16803-75-1
• Molecular Formula: C₁₁H₁₂Br₂N₂O₅
• Molecular Weight: 412.033
• Mol File: 16803-75-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BROMAMPHENICOL(CAS DataBase Reference)
• NIST Chemistry Reference: BROMAMPHENICOL(16803-75-1)
• EPA Substance Registry System: BROMAMPHENICOL(16803-75-1)

Safety Data

• Hazardous Substances Data: 16803-75-1(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 16803-75-1 differently. You can refer to the following data:
1. Bromamphenicol is a semi-synthetic chloramphenicol analogue in which the dichloroacetamide is replaced with dibromoacetamide, first reported in 1950. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome.
2. Bromamphenicol is a semi-synthetic chloramphenicol analogue first reported in 1950, in which the dichloroacetamide is replaced with dibromoacetamide. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome.

Upstream product

• 6482-26-4 methyl dibromoacetate 
• 119-62-0 (+/-)-threo-1-(4-nitro-phenyl)-2-amino-1,3-propanediol