168034-50-2Relevant academic research and scientific papers
A novel approach to 2,4-ethanoproline
Grygorenko, Oleksandr O.,Komarov, Igor V.,Cativiela, Carlos
experimental part, p. 1433 - 1436 (2009/12/03)
A novel approach to 2-azabicyclo[2.2.1]heptane-1-carboxylic acid (2,4-ethanoproline) is reported starting from (2S,4R)-4-hydroxyproline. The synthetic scheme consists of 10 steps and results in 22% total yield of the title compound. Enantiomeric purity of the product is checked by chiral stationary phase HPLC.
