168080-43-1 Usage
Uses
Used in Pharmaceutical Industry:
1,4-Benzodiazepin-3-one is used as a therapeutic agent for various medical conditions due to its stimulating activity on the type 2 arginine vasopressin receptor (V2 receptor). It is particularly effective in the prevention and treatment of:
Diabetes insipidus: A disorder characterized by excessive urination and thirst, caused by insufficient secretion of antidiuretic hormone (ADH) or the kidneys' inability to respond to ADH.
Nocturia (Night pollakiuria): Frequent urination during the night, which can disrupt sleep and affect quality of life.
Nocturnal enuresis: Involuntary urination during sleep, commonly known as bedwetting, affecting children and sometimes adults.
Overactive bladder: A condition where the bladder contracts involuntarily, leading to a sudden and intense urge to urinate, often resulting in urinary incontinence.
Haemophilia: A genetic disorder that impairs the body's ability to form blood clots, leading to excessive bleeding and potential complications.
Von Willebrand's disease: A bleeding disorder caused by a deficiency or dysfunction of von Willebrand factor, a protein that helps blood clot and platelets stick together.
These applications highlight the versatility and potential of 1,4-benzodiazepin-3-one in addressing a range of medical conditions, particularly those related to the regulation of fluid balance and blood clotting.
Check Digit Verification of cas no
The CAS Registry Mumber 168080-43-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,0,8 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 168080-43:
(8*1)+(7*6)+(6*8)+(5*0)+(4*8)+(3*0)+(2*4)+(1*3)=141
141 % 10 = 1
So 168080-43-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H22O5/c1-11-3-5-13-7-9-15-10-8-14-6-4-12-2/h3-10H2,1-2H3/i1D3,2D3
168080-43-1Relevant academic research and scientific papers
Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
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, (2008/06/13)
Tricyclic diazepines of the formula: STR1 wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
