168080-46-4Relevant academic research and scientific papers
Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists
Sum, Fuk-Wah,Dusza, John,Delos Santos, Efren,Grosu, George,Reich, Marvin,Du, Xumei,Albright, J. Donald,Chan, Peter,Coupet, Joseph,Ru, Xun,Mazandarani, Hossein,Saunders, Trina
, p. 2195 - 2198 (2007/10/03)
Novel tricyclic benzazepine derivatives were synthesized as arginine vasopressin (AVP) antagonists. Several tricyclic compounds showed potent antagonistic activity in rat AVP receptors V1a and V2. Derivatives containing pyrrolo-tricy
Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
-
, (2008/06/13)
Tricyclic diazepines of the formula: STR1 wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
