168132-70-5Relevant articles and documents
Synthesis of saframycins. XI. Synthetic studies toward a total synthesis of safracin A
Saito, Naoki,Harada, Shunji,Yamashita, Mihoko,Saito, Takeshi,Yamaguchi, Kentaro,Kubo, Akinori
, p. 8213 - 8230 (2007/10/02)
A synthetic strategy for the preparation of isoquinolinequinone antibiotic safracin A (1a) is outlined. Our initial strategy for the construction of the ABC ring was based on a retrosynthetic analysis. Conversion of 5 in five steps to the imide 16 was fol