16816-86-7Relevant articles and documents
Facile one-pot synthesis of tetrasubstituted N-sulfonylguanidines from sulfonamides and ureas
Wang, Fei,Yumaier, Abulimiti,Wusiman, Abudureheman
, p. 993 - 999 (2021)
A facile method for the synthesis of tetrasubstituted N-sulfonylguanidines has been developed via the direct condensation of sulfonamides and ureas in the presence of phosphoryl chloride under basic conditions. Detailed synthetic studies showed that this is a simple protocol for preparing N-sulfonylguanidines at room temperature in a short reaction time with good to excellent yields. Graphic abstract: [Figure not available: see fulltext.].