16817-34-8Relevant academic research and scientific papers
Preparation of highly functionalised benzofurans from ortho-hydroxyphenones and dichloroethylene: Applications and mechanistic investigations
Schevenels, Florian,Tinant, Bernard,Declercq, Jean-Paul,Markó, István E.
supporting information, p. 4335 - 4343 (2013/04/24)
Highly functionalised benzofurans have been prepared from ortho-hydroxyphenones and 1,1-dichloroethylene. The key intermediate, a chloromethylene furan, smoothly rearranged into the corresponding benzofuran carbaldehyde under acidic conditions. Some mechanistic investigations have been performed and several biologically active benzofurans have been synthesised. Copyright
