16825-99-3

Upstream product

• 651-80-9 1,2,4,5-tetrafluoro-3-(trifluoromethyl)benzene 
• 98-08-8 α,α,α-trifluorotoluene 

Downstream Products

• 31665-17-5 1-Trifluoromethylheptafluorocyclohexa-1,4-diene 
• 27943-60-8 1,2,3,5,5,6,6-heptafluoro-4-(trifluoromethyl)-1,3-cyclohexadiene 
• 27943-58-4 2H/4H-Dodecafluoromethylcyclohexane 
• 27943-61-9 4H-1-trifluoromethyloctafluorocyclo-hex-1-ene 
• 14100-81-3 cis 4H-1-trifluoromethyl/-decafluorocyclohexane 
• 16804-84-5 1-Trifluoromethyl-2H,4H-pentafluorocyclohexa-1,4-diene 
• 14100-80-2 trans 4H-1-trifluoromethyldecafluorocyclohexane 

Relevant academic research and scientific papers

Fluorination of tetrafluorobenzenes C6HF4R with XeF2

Replacement of hydrogen by fluorine and addition of fluorine atoms to the aromatic ring were found in the reaction of XeF2 with 1-R-2,3,4,5-tetrafluorobenzene (R = H, F, Br, NO2) or 1-R-2,3,4,6-tetrafluorobenzene (R = H, CF3) in HF or CH2Cl2-BF3·OEt2. Only fluorine addition took place in the case of 1-R-2,3,5,6-tetrafluorobenzenes (R = H, Br, CF3) or 1-Br-2,3,4,6-tetrafluorobenzene. The role of cation radicals as reactive intermediates is discusseed.