168253-07-4

Upstream product

• 168336-52-5 C₃₉H₄₄O₆Si 
• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 6207-45-0 2-(allyloxy)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran 
• 59531-24-7 2,3,4,6-tetra-O-benzyl-D-glucopyranoside 
• 13096-62-3 (3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one 
• 141196-28-3 trimethyl(((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)ethynyl)silane 

Downstream Products

• 917599-64-5 Cbz-L-Orn{4-(2,3,4,6-tetra-O-benzyl-β-D-glucosyl)[1,2,3]triazol-1-yl}-OMe 
• 1355034-73-9 C₂₃H₂₇N₃O₉ 
• 1355034-75-1 C₂₄H₂₉N₃O₉ 
• 1355034-77-3 C₂₃H₂₆ClN₃O₉ 
• 1355034-79-5 C₂₄H₂₆F₃N₃O₉ 
• 1355034-83-1 C₂₃H₂₆FN₃O₉ 
• 1355034-85-3 C₂₄H₂₉N₃O₁₀ 
• 1355034-89-7 C₂₃H₂₆N₄O₁₁ 
• 1355034-91-1 C₂₄H₂₆N₄O₉ 
• 1355034-97-7 C₂₇H₂₈FN₃O₉S 
• 1355034-74-0 C₁₅H₁₉N₃O₅ 
• 1355034-76-2 C₁₆H₂₁N₃O₅ 
• 1355034-78-4 C₁₅H₁₈ClN₃O₅ 
• 1355034-80-8 C₁₆H₁₈F₃N₃O₅ 

Relevant academic research and scientific papers

ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES

The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES

The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Facile synthesis of 1,2,3-triazole analogs of SGLT2 inhibitors by 'click chemistry'

Novel analogs of SGLT2 inhibitors containing the 1,2,3-triazole motif were designed and synthesized for urinary glucose excretion evaluation. The C-glucosides with triazole aglycone can be easily constructed by click chemistry. Most of the synthesized compounds increased urinary glucose excretion and demonstrated inhibition of glucose transport.

Total synthesis of indole-3-acetonitrile-4-methoxy-2-C-β-d- glucopyranoside. Proposal for structural revision of the natural product

Indole-3-acetonitrile-4-methoxy-2-C-β-d-glucopyranoside (1), a novel C-glycoside from Isatis indigotica with important cytotoxic activity, has been prepared in ten steps from ethynyl-β-C-glycoside 3 and 2-iodo-3-nitrophenyl acetate 6. Key steps in the synthesis include a Sonogashira coupling and a CuI-mediated indole formation. NMR spectroscopic data for synthetic 1 differs from that reported for the natural product. A revised structure for the natural product, containing an alternate carbohydrate substituent, is proposed. The Royal Society of Chemistry 2012.

ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS

This invention provides cholesterol absorption inhibitors of Formula (I), and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.

15. Oligosaccharide Analogues of Polysaccharides. Part 2. Regioselective Deprotection of Monosaccharide-Derived Monomers and Dimers

The Me3Si-C(1) bond of the bis-(trimethylsilyl)ethynylated anhydroalditol 2 is selectively cleaved with BuLi to yield 3/4, while AgNO2/KCN in MeOH cleaves the Me3Si-C(2') bond, leading to 5 (Scheme 1).Both Me3Si groups are removed with NaOH in MeOH (->7),