1682653-80-0
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Basic information
- Product Name: Tetrazine-PEG5-NHS ester
- Synonyms: Tetrazine-PEG5-NHS ester;Tetrazine-PEG5-NHS ester >=95%
- CAS NO:1682653-80-0
- Molecular Formula: C27H36N6O10
- Molecular Weight: 604.60894
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1682653-80-0.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20°C
- Solubility: N/A
- CAS DataBase Reference: Tetrazine-PEG5-NHS ester(CAS DataBase Reference)
- NIST Chemistry Reference: Tetrazine-PEG5-NHS ester(1682653-80-0)
- EPA Substance Registry System: Tetrazine-PEG5-NHS ester(1682653-80-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1682653-80-0(Hazardous Substances Data)
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1682653-80-0 Usage
Description
Tetrazine-PEG5-NHS Ester is a PEG linker containing a tetrazine group and an NHS ester which is very reactive with amine(NH2)-containing molecule. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).Uses
Tetrazine-PEG5-NHS ester (Tz-PEG5-NHS) can be used in click chemistry applications such as the preparation of chitosan-polyacrylamide microspheres utilizing selective tetrazine-trans-cyclooctene (Tz-TCO) ligation and the construction of copper-64 radiolabeled antibody by the click reaction.General Description
Tetrazine-PEG5-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and tetrazine, which is reactive to trans-cyclooctenes. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics, generally at least 10-fold faster compared to methyl substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.Check Digit Verification of cas no
The CAS Registry Mumber 1682653-80-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,8,2,6,5 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.Calculate Digit Verification of CAS Registry Number 1682653-80:
(9*1)+(8*6)+(7*8)+(6*2)+(5*6)+(4*5)+(3*3)+(2*8)+(1*0)=200
200 % 10 = 0
So 1682653-80-0 is a valid CAS Registry Number.
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1682653-80-0Downstream Products
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Tetrazine-PEG5-NHS ester
