168316-95-8

Basic information

• Product Name: SPINOSAD
• Synonyms: Mixture of Spinosyn A and Spinosyn D;Spinosad [iso];Tracer naturalyte;SPINOS;Spinosad Standard
• CAS NO: 168316-95-8
• Molecular Formula: C41H65NO10
• Molecular Weight: 731.96
• Product Categories: Miscellaneous Natural Products
• Mol File: 168316-95-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 110℃
• Boiling Point: 801.515°C at 760 mmHg
• Flash Point: 438.541°C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.54
• Storage Temp.: 0-6°C
• CAS DataBase Reference: SPINOSAD(CAS DataBase Reference)
• NIST Chemistry Reference: SPINOSAD(168316-95-8)
• EPA Substance Registry System: SPINOSAD(168316-95-8)

Safety Data

• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 61
• RIDADR: UN3077 9/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 168316-95-8(Hazardous Substances Data)

Usage

Description

Spinosad is a naturally-occurring insecticide found in the the soil bacterium S. spinosa. It is a mixture of the macrocyclic lactones spinosyn A and spinosyn D , which act as agonists of insect nicotinic acetylcholinesterase receptors (nAChRs). Oral administration of spinosad induces toxicity in fruit flies including C. capitata, B. curcurbitae, and B. dorsalis (LC50s = 2.8-4.2, 4.3-5.5, and 3.1-3.3 μg/ml, respectively) but has low toxicity in vertebrates. It also inhibits canine P-glycoprotein (P-gp; IC50 = 0.2 μg/ml). Formulations containing spinosad have been used in the agricultural and veterinary control of insects.

Uses

Insecticide.

Definition

Isolated from Saccharopolyspora spinosa (Actinomycetes).

Hazard

A poison by inhalation. Moderately toxic by ingestion.

InChI:InChI=1/C41H65NO10/c1-10-26-12-11-13-34(52-36-17-16-33(42(5)6)23(3)48-36)22(2)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(47-9)39(46-8)38(45-7)24(4)49-41/h14-15,20,22-31,33-34,36,38-41H,10-13,16-19,21H2,1-9H3/t22-,23?,24?,25?,26?,27?,28-,29-,30?,31+,33?,34?,36?,38?,39?,40?,41?/m1/s1