168429-36-5Relevant academic research and scientific papers
The novel skeletal rearrangement of cyclopentanones into hydroazulenones via a radical process and its application to the formal synthesis of damsinic acid
Nishida, Atsushi,Miyoshi, Irie,Ogasawara, Yukie,Nagumo, Shinji,Kawahara, Norio,Nishida, Mayumi,Takayanagi, Hiroaki
, p. 9241 - 9257 (2007/10/03)
A new skeletal rearrangement of cyclopentanones with pentynyl side chains into hydroazulene compounds via a radical process was developed. The presence of a triethylsilyloxy group at the α-position of the cyclopentanone was found to increase the reactivity. Except for this, there was no limitation of the reaction: The reaction was also applied to synthetic studies of damsinic acid, which was isolated from Ambrosia ambrosioides (Cav.) Payne along with damsin. (C) 2000 Elsevier Science Ltd.
