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CV 15959, also known as O-Desethyl Candesartan, is a metabolite of Candesartan (C175575) found in human blood plasma and urine. It is derived from the parent drug Candesartan, which is an angiotensin II receptor blocker (ARB) used to treat hypertension and heart failure.

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  • 168434-02-4 Structure
  • Basic information

    1. Product Name: CV 15959
    2. Synonyms: 2,3-Dihydro-2-oxo-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]- 4-yl]Methyl]-1H-benziMidazole-4-carboxylic Acid;2,3-Dihydro-2-oxo-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-benziMidazole-4-carboxylic Acid;CV 15959;O-Desethyl Candesartan
    3. CAS NO:168434-02-4
    4. Molecular Formula: C22H15N6O3
    5. Molecular Weight: 411.3929
    6. EINECS: N/A
    7. Product Categories: Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 168434-02-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.464±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator
    8. Solubility: DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated)
    9. PKA: 3.75±0.20(Predicted)
    10. CAS DataBase Reference: CV 15959(CAS DataBase Reference)
    11. NIST Chemistry Reference: CV 15959(168434-02-4)
    12. EPA Substance Registry System: CV 15959(168434-02-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 168434-02-4(Hazardous Substances Data)

168434-02-4 Usage

Uses

Used in Pharmaceutical Industry:
CV 15959 is used as a metabolite for understanding the pharmacokinetics and pharmacodynamics of Candesartan in the human body. Its presence in blood plasma and urine helps researchers and clinicians evaluate the drug's metabolism, efficacy, and safety profile.
Used in Research and Development:
CV 15959 is used as a research compound in the development of new drugs and therapies related to hypertension and heart failure. Its study contributes to the understanding of the underlying mechanisms of action and potential side effects of Candesartan and other ARBs.
Used in Quality Control:
CV 15959 is used as a reference material for quality control in the pharmaceutical industry. It helps ensure the purity, potency, and consistency of Candesartan and its related products, contributing to the overall safety and effectiveness of these medications.

Check Digit Verification of cas no

The CAS Registry Mumber 168434-02-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,4,3 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 168434-02:
(8*1)+(7*6)+(6*8)+(5*4)+(4*3)+(3*4)+(2*0)+(1*2)=144
144 % 10 = 4
So 168434-02-4 is a valid CAS Registry Number.

168434-02-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1H-benzimidazole-4-carboxylic acid

1.2 Other means of identification

Product number -
Other names O-Desethyl Candesartan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:168434-02-4 SDS

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