16846-34-7 Usage
Uses
Used in Pharmaceutical Industry:
Turimycin H-5 is used as an antibiotic for the treatment of bacterial infections. Its broad-spectrum activity makes it effective against a wide range of bacterial pathogens, including those that are resistant to conventional antibiotics. The potent antimicrobial properties of Turimycin H-5 contribute to its potential use in the development of new drugs to address the growing issue of antibiotic resistance.
Used in Animal Health:
In the animal health industry, Turimycin H-5 is used as a veterinary product for the control of various bacterial infections in livestock and poultry. Its effectiveness against both Gram-positive and Gram-negative bacteria makes it a valuable tool in maintaining the health of animals and preventing the spread of infectious diseases.
Used in Research and Development:
Due to its unique chemical structure and potent antimicrobial activity, Turimycin H-5 is also used in research and development for the discovery of new antibiotics and the study of bacterial resistance mechanisms. Its potential applications in this field may lead to the development of novel therapeutic strategies to combat drug-resistant infections.
Biological Activity
leucomycin a1, a major metabolite extracted from the leucomycin complex, is a major macrocyclic lactone antibiotics produced by streptomyces kitasatoensis.leucomycin a1 is one of the more potent members of leucomycin complex. leucomycin complex (kitasamycin) is effective against a wide spectrum of pathogens, such as gram-positive bacteria, gram-negative cocci, mycoplasma, and leptospira. leucomycin complex has been used as an animal health product for control of gram positive bacteria, gram negative cocci, mycoplasma, and leptospira. until now, little is known about the activity of individual analogues within the complex. at a concentration of 1.56μg/ml, kitasamycin inhibited all isolates of diplococcus pneumonia [2]. each component of leucomycins potently inhibited the growth of gram-positive bacteria and showed not so strong activity against the gram-negative bacteria. each component showed the same tendency towards the antibacterial spectrum [3].
references
[1] hata t, sano y, ohki n, et al. leucomycin, a new antibiotic[j]. the journal of antibiotics, 1953, 6(2): 87-89.[2] balducci y, bodey g p. in vitro activity of kitasamycin against gram-positive cocci[j]. the journal of antibiotics, 1974, 27(7): 516-519.[3] omura s, katagiri m, umezawa i, et al. structure-biological activities relationships among leucomycins and their derivatives[j]. the journal of antibiotics, 1968, 21(9): 532-538.
Check Digit Verification of cas no
The CAS Registry Mumber 16846-34-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,4 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16846-34:
(7*1)+(6*6)+(5*8)+(4*4)+(3*6)+(2*3)+(1*4)=127
127 % 10 = 7
So 16846-34-7 is a valid CAS Registry Number.
InChI:InChI=1/C40H67NO14/c1-22(2)18-30(45)53-38-26(6)51-32(21-40(38,7)48)54-35-25(5)52-39(34(47)33(35)41(8)9)55-36-27(16-17-42)19-23(3)28(43)15-13-11-12-14-24(4)50-31(46)20-29(44)37(36)49-10/h11-13,15,17,22-29,32-39,43-44,47-48H,14,16,18-21H2,1-10H3/b12-11+,15-13+/t23-,24-,25-,26+,27+,28+,29-,32+,33-,34-,35-,36+,37+,38+,39+,40-/m1/s1