168644-93-7 Usage
General Description
2,4,5-Trifluorobenzyl amine is a chemical compound with the molecular formula C7H6F3N. As the name suggests, it is composed of a benzene ring with three fluorine atoms at positions 2, 4, and 5, and an amine functional group (NH2) attached at the 1-position. 2,4,5-TRIFLUOROBENZYL AMINE is commonly used in organic synthesis as a building block for the production of various pharmaceuticals, agrochemicals, and fine chemicals. It can also be utilized as a reagent in the synthesis of heterocyclic compounds, specifically in the formation of pyrazole and pyrazoline derivatives. Additionally, 2,4,5-trifluorobenzyl amine has been studied for its potential use as a ligand in coordination chemistry and as a building block for the development of fluorescent organic materials.
Check Digit Verification of cas no
The CAS Registry Mumber 168644-93-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,6,4 and 4 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 168644-93:
(8*1)+(7*6)+(6*8)+(5*6)+(4*4)+(3*4)+(2*9)+(1*3)=177
177 % 10 = 7
So 168644-93-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F3N/c8-5-2-7(10)6(9)1-4(5)3-11/h1-2H,3,11H2
168644-93-7Relevant articles and documents
The pattern of fluorine substitution affects binding affinity in a small library of fluoroaromatic inhibitors for carbonic anhydrase
Doyon, Jeffrey B.,Jain, Ahamindra
, p. 183 - 185 (2008/02/11)
(equation presented) A library of fluoroaromatic inhibitors of carbonic anhydrase has been found to bind in a manner dependent on both hydrophobicity and the pattern of substitution of the fluoroaromatic ring. All of the compounds in the library bind to the protein with Kd 3 nM. We have inferred two distinct binding modes from our data, which suggest two types of interactions that should be considered when designing fluorinated drugs.
