(ASP371)-TYROSINASE (369-377) (HUMAN) is a specific fragment of the human tyrosinase enzyme that includes aspartate at position 371. Tyrosinase is a crucial enzyme involved in the initial steps of melanin biosynthesis, which is responsible for skin pigmentation and provides photoprotection against harmful UV rays. This particular fragment may play a significant role in the enzyme's structure and function, and studying it could lead to insights into pigmentation-related medical conditions and potential therapeutic interventions for melanoma.
168650-46-2
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Basic information
- Product Name: (ASP371)-TYROSINASE (369-377) (HUMAN)
- Synonyms: [ASP370]-TYROSINASE (368-376);(ASP371)-TYROSINASE (369-377) (HUMAN);ASP371, TYROSINASE 369-777, HUMAN;H-TYR-MET-ASP-GLY-THR-MET-SER-GLN-VAL-OH;TYR-MET-ASP-GLY-THR-MET-SER-GLN-VAL;YMDGTMSQV;CMM8;OCA1A
- CAS NO:168650-46-2
- Molecular Formula: C42H66N10O16S2
- Molecular Weight: 1031.16
- EINECS: N/A
- Product Categories: Peptide
- Mol File: 168650-46-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 1578.178 °C at 760 mmHg
- Flash Point: 908.249 °C
- Appearance: white/
- Density: 1.375 g/cm3
- Refractive Index: N/A
- Storage Temp.: -15°C
- Solubility: deionized water: soluble
- CAS DataBase Reference: (ASP371)-TYROSINASE (369-377) (HUMAN)(CAS DataBase Reference)
- NIST Chemistry Reference: (ASP371)-TYROSINASE (369-377) (HUMAN)(168650-46-2)
- EPA Substance Registry System: (ASP371)-TYROSINASE (369-377) (HUMAN)(168650-46-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 168650-46-2(Hazardous Substances Data)
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168650-46-2 Usage
Uses
Used in Medical Research:(ASP371)-TYROSINASE (369-377) (HUMAN) is used as a research subject for understanding the structural and functional roles of tyrosinase in melanin biosynthesis. This knowledge can contribute to the development of treatments for pigmentation-related medical conditions such as albinism and vitiligo.
Used in Cancer Therapy Development:
(ASP371)-TYROSINASE (369-377) (HUMAN) is used as a target in the development of treatments for melanoma, a type of skin cancer. Since tyrosinase is excessively active in melanoma cells, studying this specific fragment could help in designing targeted therapies to inhibit its activity, potentially leading to more effective treatments for this type of cancer.
Used in Drug Delivery Systems:
(ASP371)-TYROSINASE (369-377) (HUMAN) is used as a potential component in the design of drug delivery systems for targeted therapies. By understanding the interactions of this fragment with other molecules, researchers may develop novel drug delivery platforms that can specifically target melanoma cells, improving the efficacy and reducing the side effects of cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 168650-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,6,5 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.Calculate Digit Verification of CAS Registry Number 168650-46:
(8*1)+(7*6)+(6*8)+(5*6)+(4*5)+(3*0)+(2*4)+(1*6)=162
162 % 10 = 2
So 168650-46-2 is a valid CAS Registry Number.
168650-46-2Upstream product
168650-46-2Downstream Products
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(ASP371)-TYROSINASE (369-377) (HUMAN)
