16867-31-5

Basic information

• Product Name: 3-Ethyl-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• Synonyms: 3-Ethyl-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;M 6791
• CAS NO: 16867-31-5
• Molecular Formula: C11H12N2O
• Molecular Weight: 188.22578
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 16867-31-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Solubility: Ethanol, Methanol
• CAS DataBase Reference: 3-Ethyl-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethyl-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one(16867-31-5)
• EPA Substance Registry System: 3-Ethyl-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one(16867-31-5)

Safety Data

• Hazardous Substances Data: 16867-31-5(Hazardous Substances Data)

Usage

Uses

Intermediate in the preparation of Risperidone impurities.

Upstream product

• 504-29-0 2-aminopyridine 
• 51756-08-2 methyl 2-ethyl-3-oxobutanoate 

Downstream Products

• 70381-58-7 2-Methyl-3-ethyl-6,7,8,9-tetrahydro-4H-pyrido<1,2-a>pyrimidin-4-on 

Relevant articles and documents

Solvent-free synthesis of 4H-Pyrido[1,2-a]pyrimidin-4-ones catalyzed by BiCl3: A green route to a privileged backbone

An extensive array of 4H-pyrido[1,2-a]pyrimidin-4-ones have been synthesized from commercially available 2-aminopyridines and β-oxo esters with excellent yields under solvent-free conditions. The reaction, catalyzed by cheap and nontoxic BiCl3,