16867-47-3Relevant articles and documents
Studies on synthesis, infrared and fluorescence spectra of new europium (III) and terbium (III) complexes with an β-diketonate-type ligand
Tai, Xi-Shi,Tan, Min-Yu
, p. 1767 - 1770 (2005)
A new β-diketonate-type ligand, N-(2-amino-6-methyl-pyridinyl) ketoacetamide (L) and its complexes with europium (III) and terbium (III) were synthesized. The complexes were characterized by elemental analysis, infrared spectra and conductivity. The europium (III) and terbium (III)-ions were found to coordinate to the CO oxygen atoms and pyridine nitrogen atoms. The fluorescence properties of these complexes in solid, DMF and CH3OH were studied. The solvent factors influencing the fluorescent intensity are discussed.
Synthesis and pharmacological activities of 1,8-naphthyridine derivatives.
Leonard, Joseph Thomas,Gangadhar, Revuluri,Gnanasam, Sundararaj Kishore,Ramachandran, Somasundaram,Saravanan, Muniyandy,Sridhar, Seshaiah Krishnan
, p. 798 - 802 (2007/10/03)
In the present study, a series of 2-substituted-4-methyl-7-amino/4,7-dimethyl-1,8-naphthyridines were synthesized and characterized by IR, 1H-NMR and elemental analysis. The compounds were investigated for anticonvulsant (125, 250 mg/kg), cardiac and antimicrobial activities. The compounds were screened for antibacterial activity against gram (+) bacteria (Staphylococcus epidermidis, Bacillus subtilis, Enterococcusfaecalis and Micrococcus luteus) and gram (-) bacteria (Proteus vulgaris, Pseudomonas aeruginosa, Escherichia coli and Salmonella typhi). All the compounds except 2-(3'-phenylaminopropyloxy)-4-methyl-7-amino-1,8-naphthyridine exhibited significant anticonvulsant activity. The anticonvulsant activity of 2-(3-morpholino-2'-hydroxypropyloxy)-4-methyl-7-amino-1,8-naphthyridine, 2-(3'-diphenylamino-2'-hydroxypropyloxy)-4-methyl-7-amino-1,8-naphthyridine and 2-(3'-diethanolamino-propyloxy)-4,7-dimethy-1,8-naphthyridine at the dose of 250 mg/kg were found to be equivalent to diazepam (5 mg/kg). Sympathetic blocking activity was observed with 2-(3'-phenylamino-2'-hydroxypropyloxy)-4-methyl-7-amino-1,8-naphthyridine, 2-(3'-diethanolamino-2'-hydroxypropyloxy)-4-methyl-7-amino-1,8-naphthyridine and 2-(3'-diphenylamino-2'-hydroxypropyloxy)-4-methyl-7-amino-1,8-naphthyridine only. All the compounds were devoid of antibacterial activity against the tested bacteria.
Synthesis and biological activity of some pyridine substituted heterocyclic compounds
Abdel-Aziz
, p. 122 - 127 (2007/10/03)
Some pyridine substituted heterocyclic compounds and their derivatives such as, imidazolone, quinazolone, benzimidazole, phthalimide, thioxopyrimidindione, pyrazole, 1,2,4-triazinone and thiazolidinone (IV-XXVII) have been prepared and screened for their antibacterial and antifungal activities, which gave encouraging results. The structures of the products have been verified by elemental analysis and spectral data (IR, UV, 1H NMR and mass).