16876-69-0 Usage
Uses
Used in Pharmaceutical Industry:
Z-γ-Abu-NH-cyclohexyl is used as a GABA analog for its potential inhibitory effects on the central nervous system, which could be beneficial in the development of treatments for neurological disorders.
Used in Medicinal Chemistry:
Z-γ-Abu-NH-cyclohexyl is used as a pharmacological agent for its potential therapeutic applications, particularly in the context of neurological conditions where modulation of the central nervous system is required.
Used in Drug Development:
Z-γ-Abu-NH-cyclohexyl is used as a compound in the development of new drugs, leveraging its GABAergic properties to explore its efficacy in managing neurological symptoms and disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 16876-69-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,7 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 16876-69:
(7*1)+(6*6)+(5*8)+(4*7)+(3*6)+(2*6)+(1*9)=150
150 % 10 = 0
So 16876-69-0 is a valid CAS Registry Number.
16876-69-0Relevant academic research and scientific papers
A Mechanism for bitter Taste Sensibility in Peptides
Ishibashi, Norio,Kouge, Katsushige,Shinoda,Ichizo,Kanehisa, Hidenori,Okai, Hideo
, p. 819 - 828 (2007/10/02)
To estimate the steric distance between the bitter taste determinant sites in peptides, some cyclic dipeptides, amino acid anilides, amino acid cyclohexylamides, and benzoyl amino acids were synthesized and their tastes were evaluated.The diketopiperazine ring of cyclic dipeptides acted as a bitter taste determinant site due to its hydrophobicity.The steric distance between 2 sites was estimated as 4.1 Angstroem from the molecule models of cyclic dipeptides composed of typical amino acids in the bitter peptides.Due to the hypothesis of two bitter taste determinant sites, which bind with the bitter taste receptor via a "binding unit" and a "stimulating unit," a mechanism for the bitterness in peptides was postulated.
