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5-FLUORO-3-NITRO-2-METHYLANILINE is a chemical compound characterized by the presence of a fluorine atom, a nitro group, and a methyl group attached to an aniline ring. It is recognized for its high reactivity and serves as a versatile precursor in organic synthesis, with potential applications in the development of pharmaceuticals, agrochemicals, and dyes. The unique chemical structure of 5-FLUORO-3-NITRO-2-METHYLANILINE also positions it as a promising candidate for research in medicinal chemistry, given its potential pharmacological properties.

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  • 168770-44-3 Structure
  • Basic information

    1. Product Name: 5-FLUORO-3-NITRO-2-METHYLANILINE
    2. Synonyms: 5-FLUORO-3-NITRO-2-METHYLANILINE;5-FLURO-3-NITRO-2-METHYLANILINE;5-Fluoro-2-Methyl-3-nitroaniline;2-amino-4-fluoro-6-nitro-toluene
    3. CAS NO:168770-44-3
    4. Molecular Formula: C7H7FN2O2
    5. Molecular Weight: 170.1410832
    6. EINECS: 200-258-5
    7. Product Categories: N/A
    8. Mol File: 168770-44-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 311.5±37.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.371±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: 1.09±0.10(Predicted)
    10. CAS DataBase Reference: 5-FLUORO-3-NITRO-2-METHYLANILINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-FLUORO-3-NITRO-2-METHYLANILINE(168770-44-3)
    12. EPA Substance Registry System: 5-FLUORO-3-NITRO-2-METHYLANILINE(168770-44-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 168770-44-3(Hazardous Substances Data)

168770-44-3 Usage

Uses

Used in Pharmaceutical Industry:
5-FLUORO-3-NITRO-2-METHYLANILINE is used as an intermediate in the synthesis of various pharmaceutical compounds for its reactivity and structural properties that can be leveraged to create new drugs with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 5-FLUORO-3-NITRO-2-METHYLANILINE is utilized as a precursor in the development of agrochemicals, potentially contributing to the creation of new pesticides or herbicides that can enhance crop protection and yield.
Used in Dye Industry:
5-FLUORO-3-NITRO-2-METHYLANILINE is employed as a building block in the production of dyes, where its chemical structure can be manipulated to produce a range of colors and properties suitable for various applications, including textiles and other industrial uses.
Used in Research and Development:
5-FLUORO-3-NITRO-2-METHYLANILINE is used as a subject of research in medicinal chemistry, where its unique structure and reactivity are explored to understand its potential pharmacological properties and to develop new therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 168770-44-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,7,7 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 168770-44:
(8*1)+(7*6)+(6*8)+(5*7)+(4*7)+(3*0)+(2*4)+(1*4)=173
173 % 10 = 3
So 168770-44-3 is a valid CAS Registry Number.

168770-44-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Fluoro-2-methyl-3-nitroaniline

1.2 Other means of identification

Product number -
Other names 5-fluoro-2-methyl-3-nitroaniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:168770-44-3 SDS

168770-44-3Relevant articles and documents

QUINAZOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS

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Paragraph 0121; 0122, (2018/12/04)

Disclosed are a quinazolinone derivative, a preparation method therefor, a pharmaceutical composition, and applications. Provided are a compound represented by formula I, a pharmaceutically acceptable salt, a solvate, a crystal form, a eutectic crystal, a

Indazole compounds and application thereof to preparation of IDO inhibitors

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, (2018/11/04)

The invention discloses indazole compounds as shown in a formula (i) or (II) which is described in the specification, and a preparation method thereof, and application of the compounds as IDO inhibitors. The compounds provided by the invention can be used for preventing and/or treating a plurality of diseases, such as Alzheimer's disease, cataract, infections related to cellular immune activation,autoimmune diseases, AIDS, cancers, depression, the metabolic disorder of tryptophan or the like.

Indazole compounds containing nitrogen substituents, and application of same as IDO inhibitors

-

, (2018/11/03)

The invention discloses nitrogen substituent-containing indazole compounds as shown in a formula (I) which is described in the specification, a preparation method for the compounds, and application ofthe compounds as IDO inhibitors. The compounds provided by the invention can be used for preventing and/or treating a plurality of diseases, such as Alzheimer's disease, cataract, infections relatedto cellular immune activation, autoimmune diseases, AIDS, cancers, depression, the metabolic disorder of tryptophan or the like.

MINERALOCORTICOID RECEPTOR ANTAGONISTS

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, (2014/02/15)

The present invention is directed to compounds of the Formula I: as well as pharmaceutically acceptable salts thereof, that may be useful for treating aldosterone-mediated diseases. The invention furthermore relates to specific diastereomers and enantiome

SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

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Page/Page column 153; 154, (2010/11/18)

The invention relates to substituted aromatic carboxamide and urea derivatives, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions (formula (I)).

INDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS

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, (2008/12/07)

The present invention relates to indazole derivatives of the following formula I, which can be used as vanilloid receptor ligands, processes for their preparation, and their use in treating diseases, conditions and/or disorders modulated by vanilloid receptors. (I)

7-(2-IMIDAZOLINYLAMINO)QUINOLINE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS

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, (2008/06/13)

This invention involves involves the use of compounds having the following structure: STR1 wherein: (a) R is unsubstituted C 1-C. sub.3 alkanyl or alkenyl; and(b) R' is selected from hydrogen; unsubstituted C 1-C 3 alkanyl or alkenyl; unsubstituted

7-(2-IMIDAZOLINYLAMINO)QUINOLINE COMPOUNDS USEFUL AS ALPHA-2-ADRENOCEPTOR AGONISTS

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, (2008/06/13)

The subject invention involves methods of treating nasal congestion comprising administration, to a human or lower animal in need of such treatment of a safe and effective amount of a compound having the following structure: STR1 wherein: (a) R is unsubst

7-(2-IMIDAZOLNYLAMINO) QUINOLINE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS

-

, (2008/06/13)

The subject invention involves methods of treating nasal congestion comprising administration, to a human or lower animal in need of such treatment of a safe and effective amount of a compound having the following structure: STR1 wherein: (a) R is unsubst

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