16878-94-7

Upstream product

• 90-02-8 salicylaldehyde 
• 4303-29-1 4-thioxo-2-thiazolidinone 

Downstream Products

• 63670-94-0 7-(2-hydroxy-phenyl)-5-phenyl-6-propionyl-3,5,6,7-tetrahydro-thiopyrano[2,3-d]thiazol-2-one 
• 63670-97-3 7-(2-hydroxy-phenyl)-6-nitro-5-phenyl-3,5,6,7-tetrahydro-thiopyrano[2,3-d]thiazol-2-one 
• 1531586-11-4 7-(2-hydroxyphenyl)-2-oxo-3,7-dihydro-2H-thiopyrano[2,3-d]thiazole-6-carboxylic acid 
• 1531586-13-6 ethyl 7-(2-hydroxyphenyl)-2-oxo-3,7-dihydro-2H-thiopyrano[2,3-d]thiazole-6-carboxylate 
• 63671-05-6 6-(4-chloro-phenyl)-8-(2-hydroxy-phenyl)-3,4a,7a,8-tetrahydro-pyrrolo[4',5':5,6]thiopyrano[2,3-d]thiazole-2,5,7-trione 
• 63712-95-8 8-(2-hydroxy-phenyl)-6-phenyl-3,4a,7a,8-tetrahydro-pyrrolo[4',5':5,6]thiopyrano[2,3-d]thiazole-2,5,7-trione 

Relevant academic research and scientific papers

Synthesis of fused thiopyrano[2,3-d][1,3]thiazoles via hetero-Diels-Alder reaction related tandem and domino processes

Various novel rel-(5R,5aR,11bS)-2,6-dioxo-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazole-5-carboxylic acid derivatives were synthesized via hetero-Diels-Alder reaction related acylation-based tandem processes of 5-(ortho-hyd

Tandem hetero-Diels-Alder-hemiacetal reaction in the synthesis of new chromeno[4′,3′:4,5]thiopyrano[2,3-d]thiazoles

Novel rel-(5aR,6R,11bS)-6-hydroxy-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazole-2-ones were synthesized via tandem hetero-Diels-Alder-hemiacetal reaction of 5-(2-hydroxybenzylidene)-4-thioxo-2-thiazolidinones and α,β-unsaturated aldehydes. The stereochemistry of cycloadditions was confirmed by NMR spectra and a single crystal X-ray diffraction analysis.

Arylidene Pyruvic Acids Motif in the Synthesis of New 2H,5H-Chromeno[4′,3′:4,5]thiopyrano[2,3-d]thiazoles via Tandem Hetero-Diels-Alder-Hemiacetal Reaction

We have developed a tandem hetero-Diels-Alder-hemiacetal reaction using arylidene pyruvic acids with 5-(ortho-hydroxybenzylidene)-substituted 4-thioxo-2-thiazolidinones, leading to 6-hydroxy-2-oxo-5-phenyl-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazole-6-carboxylic acids. The stereochemistry of cycloaddition was confirmed by NMR spectra and a single-crystal x-ray diffraction analysis.

Citraconic acid and its anhydride-based hetero-Diels–Alder reactions in the synthesis of new thiopyrano[2,3-d][1,3]thiazole derivatives

Novel rel-(5R,5aR,11bS)-5-methyl-2,6-dioxo-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4?,3?:4,5]thiopyrano[2,3-d][1,3]thiazole-5-carboxylic acids were synthesized in 63–72% yields via tandem acylation-hetero-Diels–Alder reaction of 5-(2-hydroxybenzylidene)-4-th

Crotonic, cynnamic, and propiolic acids motifs in the synthesis of thiopyrano[2,3-d][1,3]thiazoles via hetero-Diels-Alder reaction and related tandem processes

Various novel thiopyrano[2,3-d][1,3]thiazol-2-one-6-carboxylic acids derivatives were synthesized in 54-86% yields via hetero-Diels-Alder reactions and related acylation-based tandem processes of 5-arylidene-4-thioxo-2- thiazolidinones with crotonic, prop