16879-40-6

Usage

Uses

Used in Pharmaceutical Industry:
4,6-Dimethyl-2-iodopyrimidine serves as a crucial intermediate in the synthesis of various pharmaceuticals. Its unique structure contributes to the development of new drugs, making it an essential component in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 4,6-Dimethyl-2-iodopyrimidine is utilized as an intermediate in the production of pesticides and other agrochemicals, highlighting its versatility in chemical synthesis for different applications.
Used in Dye Production:
4,6-Dimethyl-2-iodopyrimidine is also employed in the manufacturing process of dyes, capitalizing on its chemical properties to create a range of colorants used in various industries.
Used in Organic Compounds Synthesis:
Beyond its applications in pharmaceuticals, agrochemicals, and dyes, 4,6-Dimethyl-2-iodopyrimidine is a valuable precursor in the synthesis of other organic compounds, demonstrating its broad utility in organic chemistry.

InChI:InChI=1/C6H7IN2/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3

Upstream product

• 4472-44-0 2-chloro-4,6-dimethylpyrimidine 
• 123-54-6 acetylacetone 
• 34289-60-6 4,6-dimethyl-2-hydroxy-pyrimidine hydrochloride 

Downstream Products

• 66298-36-0 4,6-dimethyl-6-phenylethynylpyrimidine 
• 1488300-13-5 4-[7-(4,6-dimethylpyrimidin-2-yl)-9,9-dihexyl-9H-fluoren-2-yl]-N,N-dimethylaniline 
• 1488300-30-6 4-({7-[(4,6-dimethylpyrimidin-2-yl)ethynyl]-9,9-dihexyl-9H-fluoren-2-yl}ethynyl)-N,N-dimethylaniline 
• 1581300-16-4 (E,E)-4,6-bis(4-dimethylaminostyryl)-2-iodopyrimidine 
• 1581300-26-6 N,N-bis(4-iodophenyl)-4-[4-bis(E,E)-{4,6-(dibutylaminostyryl)pyrimidin-2-yl}ethynyl]aniline 
• 1581300-25-5 N,N-bis(4-iodophenyl)-4-[4-bis(E,E)-{4,6-(dimethylaminostyryl)pyrimidin-2-yl}ethynyl]aniline 
• 1581300-22-2 (E,E)-4,6-bis(4-N-dibutylaminostyryl)-2-ethynylpyrimidine 
• 1581300-20-0 (E,E)-4,6-bis(4-dimethylaminostyryl)-2-ethynylpyrimidine 
• 1581300-23-3 C₂₇H₂₈N₂O₂Si 
• 1581300-24-4 (E,E)-4,6-bis(4-methoxystyryl)-2-ethynylpyrimidine 
• 1581300-21-1 C₄₁H₅₈N₄Si 
• 1581300-19-7 C₂₉H₃₄N₄Si 
• 1581300-11-9 tris[4-{2-(4,6-dimethylpyrimidin-2-yl)ethynylpheny}]amine 
• 108-79-2 4,6-dimethyl-2(1H)-pyrimidinone 

Relevant academic research and scientific papers

Improved synthesis of 2,2′-bipyrimidine

A high-yield synthesis was developed for the preparation of 2,2′-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4′,6,6′-tetramethyl-2,2′-bipyrimidine (2) and 5,5′-dibromo-2,2′-bipyrimidine (3).

RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF

Compounds of Formulas (I), (IIA) and (IIIA) are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formulas (I), (IIA) and (IIIA) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.