1688-95-5

Usage

Uses

Used in Pharmaceutical Research:
4-methylpiperazine-1-sulfonyl chloride is used as a building block for the synthesis of various piperazine-based compounds with diverse biological activities. Its ability to participate in nucleophilic substitution reactions makes it a valuable compound for drug discovery and development.
Used in Organic Synthesis:
4-methylpiperazine-1-sulfonyl chloride is used as a versatile intermediate in the synthesis of a wide range of heterocyclic compounds. Its unique reactivity allows for the creation of various complex organic molecules.
Used in Production of Pharmaceuticals:
4-methylpiperazine-1-sulfonyl chloride is used as a key component in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Its role in the synthesis of biologically active compounds contributes to the development of new and effective drugs.
Used in Agrochemicals:
4-methylpiperazine-1-sulfonyl chloride is used as a building block in the synthesis of agrochemicals, contributing to the development of new and effective products for agricultural applications.
Safety Precautions:
It is important to handle 4-methylpiperazine-1-sulfonyl chloride with care, as it is a potent irritant and potentially hazardous if mishandled. Proper safety measures should be taken during its use to ensure the safety of individuals and the environment.

InChI:InChI=1/C5H11ClN2O2S/c1-7-2-4-8(5-3-7)11(6,9)10/h2-5H2,1H3

Upstream product

• 109-01-3 1-methyl-piperazine 
• 116833-23-9 4-methyl-piperazin-1-sulfonic acid 

Downstream Products

• 724444-34-2 N-(4-fluorobenzyl)-3-hydroxy-9-{methyl[(4-methylpiperazin-1-yl)sulfonyl]amino}-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxamide 
• 724444-30-8 C₂₂H₂₉FN₆O₅S 
• 724444-32-0 C₂₂H₂₉FN₆O₅S 
• 110417-56-6 2-((4-methylpiperazin-1-yl)sulfonyl)-1-phenylethan-1-one 
• 29604-19-1 N-sulfamoyl-N'-methylpiperazine 
• 946129-78-8 dimethylcarbamic acid 6-chloro-4-methyl-3-[3-(4-methylpiperazin-1-ylsulfonylamino)benzyl]-2-oxo-2H-1-benzopyran-7-yl ester 
• 873533-71-2 [[N-(4-methyl-1-piperazinyl)sulfonyl-N-(3-benzyloxybenzyl)]amino]acetic acid ethyl ester 
• 692755-64-9 4β-(4-methylpiperazin-1-yl)sulfonamido-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin 

Relevant academic research and scientific papers

Triazole compounds and their use in agriculture (by machine translation)

The present invention provides a triazole compound and its application in agriculture; in particular, the invention provides compounds of formula (A) indicated by the compound and its preparation method; the composition containing these compounds and preparation and their use as fungicides; wherein R1 , R2 , R3 , W, R4 , R5 , R6 , R7 , R8 , R9 , Ra , Rb And in the event of x has the meanings given by the invention. (by machine translation)

The sulfamide moiety affords higher inhibitory activity and oral bioavailability to a series of coumarin dual selective RAF/MEK inhibitors

Introducing a sulfamide moiety to our coumarin derivatives afforded enhanced Raf/MEK inhibitory activity concomitantly with an acceptable PK profile. Novel sulfamide 17 showed potent HCT116 cell growth inhibition (IC 50 = 8 nM) and good PK prof

Potent and selective, sulfamide-based human β3-adrenergic receptor agonists

A series of sulfamide-based analogs related to L-796568 were prepared and evaluated for their biological activity at the human β3- adrenergic receptor (AR). This modification allows for a significant reduction in molecular weight, while maintai

N-HETEROCYCLYL-SUBSTITUTED AMINO-THIAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS

Aminothiazole compounds with N-containing cycloalkyl at the 2-amino position which are represented by the Formula (I), or a pharmaceutically acceptable prodrug of said compound, or pharmaceutically acceptable salt of said compound, modulate and/or inhibit the cell proliferation and activity of protein kinases.

ENDOTHELIN CONVERTING ENZYME INHIBITORS

Compounds are disclosed which inhibit endothelin converting enzyme. These compounds are useful for treating hypertension, congestive heart failure, myocardial infarction, reperfusion injury, coronary angina, cerebral vasospasm, acute renal failure, non-steroidal antiinflammatory drug induced gastric ulceration, cyclosporin induced nephrotoxicity, endotoxin-induced toxicity, asthma and atherosclerosis.