168834-43-3Relevant articles and documents
Octahedral Ruthenium Complex with Exclusive Metal-Centered Chirality for Highly Effective Asymmetric Catalysis
Zheng, Yu,Tan, Yuqi,Harms, Klaus,Marsch, Michael,Riedel, Radostan,Zhang, Lilu,Meggers, Eric
supporting information, p. 4322 - 4325 (2017/04/06)
A novel ruthenium catalyst is introduced which contains solely achiral ligands and acquires its chirality entirely from octahedral centrochirality. The configurationally stable catalyst is demonstrated to catalyze the alkynylation of trifluoromethyl ketones with very high enantioselectivity (up to >99% ee) at low catalyst loadings (down to 0.2 mol%).
Electrophile-driven copper-catalyzed one-pot synthesis of 3-halogen quinoline derivatives
Cheng, Jie,Zhai, Hong,Bai, Jun,Tang, Jun,Lv, Ling,Sun, Bei
supporting information, p. 4044 - 4046 (2015/02/02)
A convenient and regioselective one-pot synthesis of 3-chloride or 3-bromide quinoline derivatives was achieved through a Grignard addition reaction by alkynyl Grignard regent to o-trifluoroacetyl aniline and a Cu(II)-catalyzed cyclization-halogenation tandem reaction with aqueous HCl or HBr as electrophilic reagent.
Alkynylation of carbonyl compounds with terminal acetylenes promoted by ZnCl2 and Et3N: Simple, mild and efficient preparation of propargylic alcohols
Jiang, Biao,Si, Yu-Gui
, p. 8323 - 8325 (2007/10/03)
A mild and efficient addition of terminal acetylenes to carbonyl compounds in the presence of ZnCl2 and Et3N gives propargylic alcohols in good to high yields.