168837-18-1

Basic information

• Product Name: 6-CHLORO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE
• Synonyms: 6-CHLORO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE;BUTTPARK 11\05-11;IMidazo[1,2-a]pyridine, 6-chloro-2-phenyl-
• CAS NO: 168837-18-1
• Molecular Formula: C₁₃H₉ClN₂
• Molecular Weight: 228.68
• Mol File: 168837-18-1.mol
• Article Data: 41

Chemical Properties

• Melting Point: 205-207℃
• Appearance: /
• Density: 1.26 g/cm³
• Refractive Index: 1.654
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.06±0.50(Predicted)
• CAS DataBase Reference: 6-CHLORO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE(168837-18-1)
• EPA Substance Registry System: 6-CHLORO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE(168837-18-1)

Safety Data

• Hazardous Substances Data: 168837-18-1(Hazardous Substances Data)

Usage

General Description

6-CHLORO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE is an organic chemical compound with the molecular formula C11H7ClN4. It is a heterocyclic compound that contains both imidazole and pyridine rings, with a chlorine atom and a phenyl group attached to the imidazole ring. 6-CHLORO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE has potential applications in the pharmaceutical industry, particularly in the development of new drugs and medications. It is important for its unique chemical structure and may have biological activities that make it suitable for use in medicinal chemistry. Additionally, it could potentially serve as a building block for the synthesis of other organic compounds and materials.

InChI:InChI=1/C13H9ClN2/c14-11-6-7-13-15-12(9-16(13)8-11)10-4-2-1-3-5-10/h1-9H

Upstream product

• 1072-98-6 5-chloro-2-pyridylamine 
• 70-11-1 α-bromoacetophenone 
• 98-86-2 acetophenone 
• 536-74-3 phenylacetylene 
• 100-42-5 styrene 
• 100-41-4 ethylbenzene 
• 19798-80-2 2-Amino-4-chloropyridine 
• 613-91-2 acetophenone oxime 
• 4636-16-2 iodoacetophenone 
• 4545-21-5 acetophenone p-toluenesulfonylhydrazone 
• 7257-94-5 1-phenyl-2-(p-tolylsulfonyloxy)ethanone 
• 75-52-5 nitromethane 
• 100-52-7 benzaldehyde 
• 102-96-5 (2-nitroethenyl)benzene 

Downstream Products

• 258338-66-8 N-(5-chloropyridin-2-yl)benzamide 
• 1310492-80-8 6-chloro-2-phenyl-3-(phenylthio)-imidazo[1,2-a]pyridine 
• 1622870-09-0 8-chloro-2,3-dibenzimidazo[1,2-α]pyridine 
• 1449488-10-1 6-chloro-3-(methylthio)-2-phenylimidazo[1,2-a]pyridine 
• 1116088-92-6 ethyl (E)-3-(6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)acrylate 
• 1116088-91-5 methyl (E)-3-(6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)acrylate 
• 1116088-93-7 benzyl (E)-3-(6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)acrylate 
• 1116088-95-9 tert-butyl (E)-3-(6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)acrylate 
• 1116088-94-8 (E)-1-(6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)pent-1-en-3-one 
• 930113-26-1 C₂₀H₁₅ClN₂ 
• 930113-34-1 C₁₈H₁₂ClN₃ 
• 365213-53-2 2-(6-chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetamide 
• 365213-62-3 (6-Chloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetic acid 
• 365213-34-9 [6-chloro-2-phenylimidazo[1,2-a]pyridin-3-ylmethyl]-dimethylamine 

Relevant articles and documents

Hypervalent iodine(III) sulfonate mediated synthesis of imidazo[1,2-a]pyridines

A direct and efficient method for the conversion of alkyl aryl ketones to imidazo[1,2-a]pyridines has been developed based on initial formation of α-organosulfonyloxy ketones and their subsequent cyclocondensation by 2-aminopyridines in one-pot conditions

Iodobenzene-catalyzed synthesis of imidazo[1,2-a]pyridines from aryl ketones with mCPBA in ionic liquid

Iodobenzene-catalyzed synthesis of imidazo[1,2-a]pyridines from aryl ketones with mCPBA as a cooxidant in ionic liquid is described. The method is simple, rapid and practical, generating Imidazo[1,2-a]pyridines from the aryl ketone without isolation of α-

Oxidation Potential-Guided Electrochemical Radical-Radical Cross-Coupling Approaches to 3-Sulfonylated Imidazopyridines and Indolizines

Oxidation potential-guided electrochemical radical-radical cross-coupling reactions between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic voltammetry measurement of substrates predicts the likelihood of successful radical-radical coupling reactions, allowing the simple and direct synthetic access to 3-sulfonylated imidazopyridines and indolizines. The developed electrochemical radical-radical cross-coupling reactions to sulfonylated N-heteroarenes boast the green synthetic nature of the reactions that are oxidant- and metal-free.

Micellar Catalysis: Visible-Light Mediated Imidazo[1,2-a]pyridine C—H Amination with N-Aminopyridinium Salt Accelerated by Surfactant in Water

A light-promoted metal-free protocol for the amination of imidazo[1,2-a]pyridines with N-aminopyridinium salt by the assistance of surfactants in water was reported, charactering mild and environmentally benign conditions, as well as great functional grou