16889-21-7

Basic information

• Product Name: 6-chloro-1H-indazol-3-amine
• Synonyms: 6-chloro-1H-indazol-3-amine;Einecs 240-925-9;3-Amino-6-chloro-1H-indazole;6-Chloro-1H-Indazol-3-Amine (6-Chloro-1H-Indazol-3-Yl)Amine;Zinc00154498
• CAS NO: 16889-21-7
• Molecular Formula: C₇H₆ClN₃
• Molecular Weight: 167.59564
• EINECS: 240-925-9
• Mol File: 16889-21-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 408.7°Cat760mmHg
• Flash Point: 201°C
• Appearance: /
• Density: 1.533g/cm³
• Vapor Pressure: 6.86E-07mmHg at 25°C
• Refractive Index: 1.777
• Storage Temp.: 2-8°C(protect from light)
• PKA: 13.72±0.40(Predicted)
• CAS DataBase Reference: 6-chloro-1H-indazol-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-1H-indazol-3-amine(16889-21-7)
• EPA Substance Registry System: 6-chloro-1H-indazol-3-amine(16889-21-7)

Safety Data

• Hazardous Substances Data: 16889-21-7(Hazardous Substances Data)

Usage

General Description

6-chloro-1H-indazol-3-amine is a chemical compound with the molecular formula C7H6ClN3. It is a chlorinated derivative of indazole, which is a heterocyclic aromatic organic compound. 6-chloro-1H-indazol-3-amine has potential applications in the pharmaceutical industry, particularly in the development of new drugs. It may also be used as a building block in organic synthesis for the creation of various other compounds. The chemical structure of 6-chloro-1H-indazol-3-amine makes it an interesting target for further research and potential industrial applications.

InChI:InChI=1/C7H6ClN3/c8-4-1-2-5-6(3-4)10-11-7(5)9/h1-3H,(H3,9,10,11)

Upstream product

• 63069-48-7 p-chloro-o-iodoaniline 
• 57381-51-8 4-chloro-2-fluorobenzonitrile 
• 6574-98-7 2,4-dichlorobenzylnitrile 
• 57381-49-4 2-bromo-4-chloro-benzonitrile 
• 131002-01-2 2-bromo-4-chlorobenzamide 

Downstream Products

• 599191-63-6 N-[6-chloro-1H-indazol-3-yl]benzenamide 
• 60329-89-7 3-amino-6-chloro-indazole-2-carboxylic acid methyl ester 
• 1263320-05-3 3-amino-N-(4-butoxyphenyl)-6-chloro-1H-indazole-1-carboxamide 
• 1263320-04-2 3-amino-N-(4-benzylphenyl)-6-chloro-1H-indazole-1-carboxamide 

Relevant articles and documents

INDAZOLE GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF

The invention provides indazole guanidine compounds that inhibit F1F0-ATPase, and methods of using indazole guanidine compounds as therapeutic agents to treat medical disorders, such as an immune disorder, inflammatory condition, or cancer.

Rational design of potent GSK3β inhibitors with selectivity for Cdk1 and Cdk2

From an HTS hit, a series of potent and selective inhibitors of GSK3β have been designed based on a Cdk2-homology model and with the help of several crystal structures of the compounds within Cdk2.

3-Aminoindazole derivatives

.Iadd.Pharmaceutical compositions having muscle relaxant and analgesic activity containing 3-aminoindazoles..Iaddend.