168910-63-2Relevant academic research and scientific papers
Selective inhibitors of Candida albicans dihydrofolate reductase: Activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines
Chan,Hong,Kuyper,Baccanari,Joyner,Tansik,Boytos,Rudolph
, p. 3608 - 3616 (2007/10/03)
The recent increase in fungal infections, especially among AIDS patients, has resulted in the need for more effective antifungal agents. In our search for such agents, we focused on developing compounds which inhibit fungal dihydrofolate reductase (DHFR).
