168966-54-9

Basic information

• Product Name: 1,2-Benzenediamine,3,4,5-trifluoro-(9CI)
• Synonyms: 1,2-Benzenediamine,3,4,5-trifluoro-(9CI);3,4,5-Trifluorobenzene-1,2-diamine;3,4,5-Trifluorophenylene-1,2-diamine, 1,2-Diamino-3,4,5-trifluorobenzene;1,2-Benzenediamine, 3,4,5-trifluoro-
• CAS NO: 168966-54-9
• Molecular Formula: C₆H₅F₃N₂
• Molecular Weight: 162.1125096
• Product Categories: HALIDE
• Mol File: 168966-54-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1,2-Benzenediamine,3,4,5-trifluoro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediamine,3,4,5-trifluoro-(9CI)(168966-54-9)
• EPA Substance Registry System: 1,2-Benzenediamine,3,4,5-trifluoro-(9CI)(168966-54-9)

Safety Data

• Hazardous Substances Data: 168966-54-9(Hazardous Substances Data)

Usage

General Description

1,2-Benzenediamine,3,4,5-trifluoro-(9CI) is a chemical compound with the molecular formula C6H5F3N2. It is commonly used in the production of various polymers and dyes, as well as in the manufacture of pharmaceuticals and agrochemicals. 1,2-Benzenediamine,3,4,5-trifluoro-(9CI) is considered to be a skin and eye irritant, and exposure to high concentrations may cause respiratory irritation or damage to the lungs. It is also considered to be potentially harmful if swallowed, and may cause adverse effects on the liver and kidneys. Additionally, 1,2-Benzenediamine,3,4,5-trifluoro-(9CI) is known to be harmful to aquatic life and can have long-lasting effects on the environment. Therefore, proper handling and disposal procedures should be followed when working with this compound to minimize its impact on human health and the environment.

Upstream product

• 882068-89-5 C₆H₃F₃N₂O₂ 
• 64-17-5 ethanol 
• 365-29-7 N-(2,3,4-trifluorophenyl)acetamide 
• 148416-38-0 6-nitro-2,3,4-trifluoroaniline 
• 3862-73-5 2,3,4-trifluoroaniline 

Downstream Products

• 1196131-58-4 5,6,7-triifluoro-2-phenyl-1H-benzimidazole 

Relevant articles and documents

Chemoenzymatic Synthesis and Antiherpes Activity of 5-Substituted 4,6-Difluorobenzimidazoles Ribo- and 2′-Deoxyribonucleosides

A series of 5,6-disubstituted benzimidazole nucleosides, obtained earlier, did not show any significant antiviral activity at relatively low cytotoxicity in vitro. In the course of our research we have succeeded in introducing an additional fluorine atom

Synthesis and potent antifungal activity against Candida species of some novel 1H-benzimidazoles

(Chemical Equation Presented) A series of 47 novel N1-alkylated- 2-aryl-5(6)-substituted-1H-benzimidazoles and their three novel indole analogues were synthesized and evaluated for in vitro antifungal activities against Candida species by the tube dilution method. The results showed that compounds 79 and 80, having pyridine at the position C-2, of benzimidazoles exhibited the greatest activity with MIC values of 6.25-3.12 μg/mL. Indole analogues 108-110 have no inhibitory activity.

Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones

Methods of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia, and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, and Down's syndrome, treating or preventing the adverse consequences of the hyperactivity of the excitatory amino acids, as well as treating anxiety, chronic pain, convulsions, and inducing anesthesia are disclosed by administering to an animal in need of such treatment an alkyl or azido-substituted 1,4-dihydroquinoxaline-2,3-dione or pharmaceutically acceptable salts thereof, which have high binding to the glycine receptor.