16897-57-7

Usage

Physical state

Colorless liquid

Usage

Primarily as a fragrance ingredient

Family

Acenaphthylene family

Classification

Cyclic alcohol

Application

Manufacturing of perfumes and scented products

Odor

Pleasant

Pharmaceutical potential

Antibacterial and antifungal properties

Importance

Significant in fragrance and pharmaceutical industries due to unique properties

Upstream product

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 63328-19-8 (1,2,3,4-tetrahydro-[1]naphthyl)-malonic acid diethyl ester 
• 79781-34-3 1,2,3,4-tetrahydronaphthalene-1-acetic acid chloride 
• 74247-18-0 ethyl 2-cyano-2-(3,4-dihydronaphthalen-1(2H)-ylidene)acetate 
• 66258-75-1 1-carboxy-1,2,3,4-tetrahydronaphthalene-1-acetic acid anhydride 
• 63328-18-7 3,4,5,10-tetrahydroacenaphthene-1-one 
• 79781-33-2 1,2,3,4-tetrahydronaphthalene-1-acetic acid methyl ester 
• 63328-17-6 2-(1,2,3,4-tetrahydronaphthalen-1-yl)acetic acid 
• 17516-09-5 1-carboxy-1,2,3,4-tetrahydronaphthalene-1-acetic acid 

Downstream Products

• 16897-56-6 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline 
• 951152-20-8 3,4-Trimethylen-inden 
• 83-32-9 acenaphthene 

Relevant academic research and scientific papers

BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF

Provided is an ORL-1 receptor agonist having improved bioavailability based on superior metabolic stability and strong and high selectivity, as compared to conventional compounds. A compound represented by the formula (I) wherein each symbol is as defined

3,4-, 4,7- and 1,4,7-Substituted indenyl-TiCl3 complexes: Synthesis and comparison of substituent effects

Me3Si-substituted indenes of type 1-SiMe3-3,4- (CH2)3C9H5 (9), 1-SiMe 3-4-R-7-R′C9H5 (11a, R = R′ = Me; 11b, R = R′ = Ph; 11c, R = Me, R′ = Ph) and 1,1′-(SiMe 3)2-4,7-Me2C9H4 (12) were synthesised as precursors for piano-stool type halfsandwich indenyl-titanium trichloride complexes. Treatment of 9, 11, and 12 with equimolar amounts of TiCU gives the complexes (η5-3,4-(CH2)3C 9H5)TiCl3 (13), (η5-4-R-7- R′C9H5)TiCl3 (14a, R = R′ = Me; 14b, R = R′ = Ph; 14c, R = Me, R′ = Ph), and (η5-1- SiMe3-4,7-Me2C9H4)TiCl3 (15), respectively, with liberation of Me3SiCl. Detailed UV/vis spectroscopic and cyclic voltammetric studies were carried out which allow a comparison of substituent effects in 13-15.

Abnormal Behaviour of Anhydrides of 1-Carboxy-1,2,3,4-tetrahydronaphthalene-1-acetic Acid and Its 7-Methyl Derivative in Presence of Anhydrous Aluminium Chloride: Synthesis of Acenaphthene and 3-Methylacenaphthene

Friedel-Crafts reaction of the anhydride of 1-carboxy-1,2,3,4-tetrahydronaphthalene-1-acetic acid (1a, R=H ) with benzene or toluene at 50-60 deg C affords 1,2,3,4-tetrahydronaphthalene-1-acetic acid (2a) and 10-carboxy-3,4,5,10-tetrahydroacenaphthene-1-one (3c).The anhydride of 1b (R=Me) similarly yields 7-methyl-1,2,3,4-tetrahydronaphthalene-1-acetic acid (2b). 2a,2b and their methyl esters have been converted into 3,4,5,10-tetrahydroacenaphthene-1-one (3a) and the 8-methyl analogue (3b) respectively. 3a and 3b on reduction afford 4a and 4b, which on dehydrogenation with Pd/C afford acenaphthene and 3-methylacenaphthene respectively. 3-Methylacenaphthene has also been synthesised by an alternate route starting from 7-methyltetralone.