168980-13-0Relevant academic research and scientific papers
Structural basis for the potent calpain inhibitory activity of peptidyl α-ketoacids
Donkor, Isaac O.,Assefa, Haregewein,Liu, Jiuyu
experimental part, p. 4346 - 4350 (2009/05/27)
A series of peptidyl α-ketoacids and α-ketoesters was synthesized and studied as μ-calpain inhibitors. Docking studies revealed that the μ-calpain inhibitory activity of the compounds is influenced by hydrogen bonding interactions and the potential for io
