169037-22-3

Basic information

• Product Name: 4,5-difluoroisatin
• CAS NO: 169037-22-3
• Molecular Weight: 183.114
• Mol File: 169037-22-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,5-difluoroisatin(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-difluoroisatin(169037-22-3)
• EPA Substance Registry System: 4,5-difluoroisatin(169037-22-3)

Safety Data

• Hazardous Substances Data: 169037-22-3(Hazardous Substances Data)

Upstream product

• 507-40-4 tert-butylhypochlorite 
• 5466-06-8 3-mercaptopropionic acid ethyl ester 
• 3863-11-4 3,4-difluoroaniline 

Relevant articles and documents

Indolo[2,1-biquinazoline-6,12-dione antibacterial compounds and methods of use thereof

Methods, compounds and compositions are provided form inhibiting the growth of pathogenic mycobacteria in vitro and of treatment of pathogenic mycobacterial infections in vivo using indolo[2,1-b]quinazoline-6,12-dione compounds of the formula (I): STR1 wherein A, B, C, D, E, F, G and H are independently selected from carbon and nitrogen, or A and B or C and D can be taken together to be nitrogen or sulfur, and the pharmaceutically acceptable salts thereof. The methods, compounds and compositons are particularly useful for inhibiting the growth of Mycobacterium tuberculosis, and may be used alone, or in combination with other anti-Mycobacterium tuberculosis agents, such as isoniazid, rifampin, pyrazinamide, rifabutin, streptomycin and ciprofloxacin, to provide new agents for the treatment of tuberculosis, including multidrug-resistant tuberculosis (MDRTB).