169044-96-6

Basic information

• Product Name: 2-Amino-5-bromo-4-methoxy-benzoic acid methyl ester
• Synonyms: 2-Amino-5-bromo-4-methoxy-benzoic acid methyl ester;Methyl 2-amino-5-bromo-4-methoxybenzoate;Methyl 2-Amino-5-Bromo-4-Methoxybenzoate(WXC00595)
• CAS NO: 169044-96-6
• Molecular Formula: C₉H₁₀BrNO₃
• Molecular Weight: 260.0846
• Mol File: 169044-96-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 2-Amino-5-bromo-4-methoxy-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-bromo-4-methoxy-benzoic acid methyl ester(169044-96-6)
• EPA Substance Registry System: 2-Amino-5-bromo-4-methoxy-benzoic acid methyl ester(169044-96-6)

Safety Data

• Hazardous Substances Data: 169044-96-6(Hazardous Substances Data)

Usage

General Description

2-Amino-5-bromo-4-methoxy-benzoic acid methyl ester is a chemical compound with the formula C9H9BrNO4. It is a methyl ester of 2-Amino-5-bromo-4-methoxy-benzoic acid and is commonly used in organic synthesis and pharmaceutical research. 2-Amino-5-bromo-4-methoxy-benzoic acid methyl ester is a white to pale yellow solid that is sparingly soluble in water but soluble in organic solvents. It is known for its potential use as a building block in the synthesis of various pharmaceutical and agrochemical products. Its structure and properties make it a valuable intermediate for the production of a wide range of useful compounds.

Upstream product

• 4294-95-5 4-methoxyanthranilic acid 
• 74-88-4 methyl iodide 
• 169045-04-9 2-amino-5-bromo-4-methoxybenzoic acid 
• 50413-30-4 methyl 2-amino-4-methoxybenzoate 

Downstream Products

• 1256955-27-7 6-bromo-4-chloro-7-methoxyquinazoline 
• 950577-05-6 6-bromo-7-methoxyquinazoline-4(3H)-one 

Relevant articles and documents

The Enantioselective Synthesis of Eburnamonine, Eucophylline, and 16′-epi-Leucophyllidine

A synthetic approach to the heterodimeric bisindole alkaloid leucophyllidine is disclosed herein. An enantioenriched lactam building block, synthesized through palladium-catalyzed asymmetric allylic alkylation, served as the precursor to both hemispheres. The eburnamonine-derived fragment was synthesized through a Bischler–Napieralski/hydrogenation approach, while the eucophylline-derived fragment was synthesized by Friedl?nder quinoline synthesis and two sequential C?H functionalization steps. A convergent Stille coupling and phenol-directed hydrogenation united the two monomeric fragments to afford 16′-epi-leucophyllidine in 21 steps from commercial material.

Imidazo[1,5-a]quinazoline-5(4H)-ketone derivative as well as preparation method and application thereof

The invention relates to an imidazo[1,5-a]quinazoline-5(4H)-ketone derivative as well as a preparation method and application thereof. The imidazo[1,5-a]quinazoline-5(4H)-ketone derivative disclosed by the invention can be used for preparing a BET protein

NOVEL BENZYLAMINO SUBSTITUTED QUINAZOLINES AND DERIVATIVES AS SOS1 INHIBITORS

The present invention encompasses compounds of formula (I), wherein the groups R1 to R7 have the meanings given in the claims and specification, their use as inhibitors of SOS1, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.