169062-92-4 Usage
General Description
Cyclomarin A is a natural product isolated from marine bacteria, known for its potent antibacterial and antifungal properties. It consists of a unique 21-membered macrolactone ring with a highly functionalized and complex structure. Cyclomarin A inhibits the growth of a wide range of bacteria, including drug-resistant strains, by disrupting their cell membrane integrity. It also demonstrates antifungal activity, making it a promising candidate for the development of new antibiotics and antifungal agents. Additionally, studies have shown that cyclomarin A exhibits low toxicity to human cells, making it a potential lead compound for the development of new pharmaceuticals to combat infectious diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 169062-92-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,0,6 and 2 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 169062-92:
(8*1)+(7*6)+(6*9)+(5*0)+(4*6)+(3*2)+(2*9)+(1*2)=154
154 % 10 = 4
So 169062-92-4 is a valid CAS Registry Number.
169062-92-4Relevant articles and documents
Total Synthesis of Cyclomarin A, a Marine Cycloheptapeptide with Anti-Tuberculosis and Anti-Malaria Activity
Barbie, Philipp,Kazmaier, Uli
supporting information, p. 204 - 207 (2016/02/03)
An efficient synthetic protocol for the stereoselective synthesis of cyclomarin A is reported. Key steps in the syntheses of the building blocks are an asymmetric chelate-enolate Claisen rearrangement, an asymmetric hydrogenation, and highly diastereosele