169106-36-9

Basic information

• Product Name: R-2-Aminododecanoic acid
• Synonyms: R-2-Aminododecanoic acid;R-dodecyline;REF DUPL: R-2-Aminododecanoic acid;R-dodecyline R-2-AMinododecanoic acid
• CAS NO: 169106-36-9
• Molecular Formula: C12H25NO2
• Molecular Weight: 215.3324
• Mol File: 169106-36-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 205 °C (decomp)
• Boiling Point: 332.8±25.0 °C(Predicted)
• Appearance: /
• Density: 0.955±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 2.55±0.24(Predicted)
• CAS DataBase Reference: R-2-Aminododecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: R-2-Aminododecanoic acid(169106-36-9)
• EPA Substance Registry System: R-2-Aminododecanoic acid(169106-36-9)

Safety Data

• Hazardous Substances Data: 169106-36-9(Hazardous Substances Data)

Usage

General Description

R-2-Aminododecanoic acid, also known as 2-Aminolauryl acid, is a long-chain fatty acid that contains an amino group. It is a white crystalline solid at room temperature and is classified as an amino acid derivative. This chemical is often used in the synthesis of pharmaceuticals and industrial chemicals, as well as in the production of surfactants and detergents. It has a wide range of applications due to its amphiphilic nature, which allows it to function as a surfactant that can lower the surface tension of liquids. Additionally, R-2-Aminododecanoic acid has potential uses in the development of bio-based polymers and as a building block for other organic compounds.

Upstream product

• 13880-54-1 (+/-)-2-amino-dodecanoic acid amide 
• 205385-74-6 2-(2-chloro-acetylamino)-dodecanoic acid 
• 35237-37-7 2-amino-dodecanoic acid 
• 2050-77-3 Iododecane 
• 634585-78-7 (R)-2-Amino-dodecanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide 
• 188070-10-2 (R)-2-(2-Chloro-acetylamino)-dodecanoic acid 
• 13880-54-1 (R)-2-amino-dodecanoic acid amide 

Downstream Products

• 168965-95-5 benzyl-R-α-hydroxy-n-dodecanoate 
• 168965-96-6 (R)-2-Trifluoromethanesulfonyloxy-dodecanoic acid benzyl ester 
• 1027301-74-1 (S)-2-{[2-(2-Amino-3-hydroxy-propyl)-phenyl]-methyl-amino}-dodecanoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 70267-25-3 (R)-2-hydroxy-dodecanoic acid 

Relevant articles and documents

The synthesis of some chiral 2-aminoalkyloxazole-4-carboxylates from isoxazol-5(2H)-ones

Ethyl 4-methyl-5-oxo-2,5-dihydroisoxazole-3-carboxylate can be N-acylated by a number of natural and synthetic phthalimidylamino acids in the presence of carbodiimides. The N-acyiated products form the corresponding oxazoles smoothly when irradiated at 300 nm in acetone. Removal of the phthalimido protecting group then gives 2-aminoalkyloxazole-4-carboxylate esters in good overall yields, and without significant racemization at any step.

Role of the hydrophobic moiety of tumor promoters. Synthesis and activity of benzolactams with alkyl substituents at various positions

We synthesized benzolactams with hydrophobic substituents at various positions as analogs of (-)-benzolactam-V8-310 ((-)-BL-V8-310, 1) which reproduces the active conformation and biological activity of teleocidins. Structure-activity data indicate that the existence of a hydrophobic region between C-2 and C-9, and the steric factor at C-8 play critical roles in the appearance of biological activities.