169217-38-3Relevant articles and documents
Detection of divinyl ether synthase in Lily-of-the-Valley (Convallaria majalis) roots
Ogorodnikova, Anna V.,Latypova, Larisa R.,Mukhitova, Fahima K.,Mukhtarova, Lucia S.,Grechkin, Alexander N.
experimental part, p. 2793 - 2798 (2009/04/11)
Incubations of linoleic acid with cell-free preparations from Lily-of-the-Valley (Convallaria majalis L., Ruscaceae) roots revealed the presence of 13-lipoxygenase and divinyl ether synthase (DES) activities. Exogenous linoleic acid was metabolized predominantly into (9Z,11E,1′E)-12-(1′-hexenyloxy)-9,11-dodecadienoic (etheroleic) acid. Its identification was confirmed by the data of ultraviolet spectroscopy, mass spectra, 1H NMR, COSY, catalytic hydrogenation. The isomeric divinyl ether (8E,1′E,3′Z)-12-(1′,3′-nonadienyloxy)-8-nonenoic (colneleic) acid was detected as a minor product. Incubations with linoleic acid hydroperoxides revealed that 13-hydroperoxide was a preferential substrate, while the 9-hydroperoxide was utilized with lesser efficiency.
Stereospecific synthesis of novel divinyl ether oxylipins by the enzyme from garlic bulbs
Grechkin,Hamberg
, p. 827 - 828 (2007/10/03)
Oxidation of (9Z,11E,13R,S)-13-hydroperoxy-9,11-octadecadienoic acid by the synthase of divinyl ethers from garlic bulbs (Allium sativum L.) was studied. The enzyme was found to be partially stereospecific, preferentially using the (13S)-epimer of hydroperoxide.
