169220-57-9

Upstream product

• 169220-56-8 (5R,6S,7S,8R)-2-allyl-6,7-bis(benzyloxy)-5-benzyloxymethyl-8-(t-butyldimethylsilyloxy)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine 
• 188476-95-1 (5R,6S,7S,8R)-6,7-bis(benzyloxy)-5-benzyloxymethyl-8-(t-butyldimethylsilyloxy)-5,6,7,8-tetrahydro-2-(2,3-dihydroxypropyl)imidazo[1,2-a]pyridine 
• 16838-89-4 2,3,5-tri-O-benzyl-α-L-ribofuranose 
• 162438-92-8 2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole 
• 162438-94-0 (5R,6S,7S,8R)-6,7-bis(benzyloxy)-5-benzyloxymethyl-5,6,7,8-tetrahydro-8-hydroxyimidazo[1,2-a]pyridine 
• 188476-92-8 (5R,6S,7S,8R)-6,7-bis(benzyloxy)-5-benzyloxymethyl-8-(t-butyldimethylsilyloxy)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine 
• 188476-94-0 (5R,6S,7S,8R)-6,7-bis(benzyloxy)-5-benzyloxymethyl-2-bromo-8-(t-butyldimethylsilyloxy)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine 

Downstream Products

• 169220-58-0 methyl (5R,6S,7S,8R)-6,7-bis(benzyloxy)-5-benzyloxymethyl-8-(t-butyldimethylsilyloxy)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-acetate 
• 188476-96-2 methyl (5R,6S,7S,8R)-6,7-bis(benzyloxy)-5-benzyloxymethyl-5,6,7,8-tetrahydro-8-hydroxyimidazo[1,2-a]pyridine-2-acetate 
• 169134-70-7 methyl (5R,6S,7S,8S)-8-azido-6,7-bis(benzyloxy)-5-benzyloxymethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-acetate 

Relevant academic research and scientific papers

The total synthesis of a glycosidase inhibitor, nagstatin

A glycosidase inhibitor, nagstatin, has been synthesized from protected L-ribofuranose through the inter- and intramolecular nucleophilic reactions of the imidazole moieties and the regioselective introduction of a carboxymethyl group.

Total synthesis of nagstatin, an n-acetyl-β-glucosaminidase inhibitor

The first enantiospecific total synthesis of nagstatin has been accomplished through the regioselective introduction of an allyl group on the imidazole ring of the de-branched nagstatin precursor followed by conversion into the carboxymethyl group, and th