Welcome to LookChem.com Sign In|Join Free


  • or


Post Buying Request

169260-97-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

169260-97-3 Usage


5-(trifluoromethyl)thiazol-2-amine is an organic compound featuring a thiazol ring with an amine group at the 2nd position and a trifluoromethyl group at the 5th position. 5-(trifluoromethyl)thiazol-2-amine is known for its potential applications in various chemical and pharmaceutical processes due to its unique structural properties.


Used in Organic Synthesis:
5-(trifluoromethyl)thiazol-2-amine is used as an organic synthesis intermediate for the creation of various complex organic molecules. Its unique structure allows it to be a versatile building block in the synthesis of a wide range of compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-(trifluoromethyl)thiazol-2-amine is utilized as a pharmaceutical intermediate. Its presence in the molecular structure can contribute to the development of new drugs with improved pharmacological properties, such as enhanced potency, selectivity, and bioavailability.
Used in Laboratory Research and Development:
5-(trifluoromethyl)thiazol-2-amine is also employed in laboratory research and development processes. It serves as a valuable tool for scientists to explore new chemical reactions, investigate the properties of novel compounds, and develop innovative synthetic methodologies.
Used in Chemical Production Process:
Finally, 5-(trifluoromethyl)thiazol-2-amine plays a role in the chemical production process, where it is used to manufacture various chemical products on a larger scale. Its application in this context highlights the compound's industrial relevance and its contribution to the chemical industry's growth and innovation.


Sodium dithionite (1.0 mmol) was added in one portion to a mixture of 2-aminothiazole (1.0 mmol), NaHCO3 (1.0 mmol) and polyfluoroalkyl iodide (1.5 mmol) in acetonitrile/water (4:1/v:v) at 5-10 °C under Ar atmosphere. The mixture was stirred until complete conversion of starting material as indicated by TLC analysis. Acetonitrile was removed under reduced pressure and water (5 mL) was added. The mixture was extracted with ethyl acetate (4.0 mL .x. 3) and the combined organic layers were dried over Na2SO4. The solvent was removed under vacuum and the residue was purified by column chromatography on silica gel (petroleum/ethyl acetate) to give the product.

Check Digit Verification of cas no

The CAS Registry Mumber 169260-97-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,2,6 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 169260-97:
163 % 10 = 3
So 169260-97-3 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017


1.1 GHS Product identifier

Product name 5-(Trifluoromethyl)thiazol-2-amine

1.2 Other means of identification

Product number -
Other names 5-(trifluoromethyl)-1,3-thiazol-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:169260-97-3 SDS

169260-97-3Relevant articles and documents



Page/Page column 49, (2012/07/14)

This invention relates to azabicyclo[4.1.0]hept-4-yl derivatives and their use as pharmaceuticals.

Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication

Stachulski, Andrew V.,Pidathala, Chandrakala,Row, Eleanor C.,Sharma, Raman,Berry, Neil G.,Iqbal, Mazhar,Bentley, Joanne,Allman, Sarah A.,Edwards, Geoffrey,Helm, Alison,Hellier, Jennifer,Korba, Brent E.,Semple, J. Edward,Rossignol, Jean-Francois

supporting information; experimental part, p. 4119 - 4132 (2011/08/05)

We report the syntheses and activities of a wide range of thiazolides [viz., 2-hydroxyaroyl-N-(thiazol-2-yl)amides] against hepatitis B virus replication, with QSAR analysis of our results. The prototypical thiazolide, nitazoxanide [2-hydroxybenzoyl-N-(5-

α- or β-Trifluoromethyl epoxysulfones: new C3 reagents for heterocyclisation

Laduron, Frederic,Janousek, Zdenek,Viehe, Heinz, G.

, p. 83 - 86 (2007/10/02)

The syntheses of α- and β-trifluoromethyl epoxysulfones 1 and 2 are described.Compound 1 reacts with nucleophiles and bis-nucleophiles to furnish trifluoromethyl ketones and trifluoromethyl heterocycles in good yield, while its isomer 2 leads to the opposite thiazole regioisomers with thioamides. - Keywords: Trifluoromethyl epoxysulfones; Heterocyclisation; Regioisomers; NMR spectroscopy; IR spectroscopy

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)


What can I do for you?
Get Best Price

Get Best Price for 169260-97-3