169280-05-1

Basic information

• Product Name: 1-Butanone, 4-chloro-1-[4-(1-chloro-1-methylethyl)phenyl]-
• CAS NO: 169280-05-1
• Molecular Formula: C13H16Cl2O
• Molecular Weight: 259.175
• Mol File: 169280-05-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 4-chloro-1-[4-(1-chloro-1-methylethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 4-chloro-1-[4-(1-chloro-1-methylethyl)phenyl]-(169280-05-1)
• EPA Substance Registry System: 1-Butanone, 4-chloro-1-[4-(1-chloro-1-methylethyl)phenyl]-(169280-05-1)

Safety Data

• Hazardous Substances Data: 169280-05-1(Hazardous Substances Data)

Upstream product

• 873072-16-3 [4-(1-chloro-1-methyl-ethyl)-phenyl]-cyclopropyl-methanone 

Downstream Products

• 169280-21-1 2-[4-(4-chloro-butyryl)-phenyl]-2-methyl-propionic acid 

Relevant articles and documents

PROCESS FOR CARBONYLATING PHENYLALKYL DERIVATIVES BY MEANS OF CARBON MONOXIDE

The invention is directed a process of preparing a compound of formula (I), wherein R1, R2, R3 and z are as defined herein.

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula whereinW represents —C(=O)— or —CH(OH)—;R1 represents hydrogen or hydroxy;R2 represents hydrogen;R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2;n is an integer of from 1 to 5;m is an integer 0 or 1;R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; andpharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, m is an integer 0.