169280-25-5

Basic information

• Product Name: 1-Butanone, 4-chloro-1-[4-(2-hydroxy-1,1-dimethylethyl)phenyl]-
• CAS NO: 169280-25-5
• Molecular Formula: C14H19ClO2
• Molecular Weight: 254.757
• Mol File: 169280-25-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 4-chloro-1-[4-(2-hydroxy-1,1-dimethylethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 4-chloro-1-[4-(2-hydroxy-1,1-dimethylethyl)phenyl]-(169280-25-5)
• EPA Substance Registry System: 1-Butanone, 4-chloro-1-[4-(2-hydroxy-1,1-dimethylethyl)phenyl]-(169280-25-5)

Safety Data

• Hazardous Substances Data: 169280-25-5(Hazardous Substances Data)

Usage

Molecular weight

238.75 g/mol
Chlorinated derivative of butanone (methyl ethyl ketone)
Substituted phenyl group present
Contains a hydroxyl group
Used in production of pharmaceuticals and agrochemicals
Used as a solvent and intermediate in organic synthesis
Studied for potential cytotoxic and antifungal properties

Upstream product

• 154477-54-0 2-[4-(4-Chloro-butyryl)-phenyl]-2-methyl-propionic acid, methyl ester 

Downstream Products

• 169280-21-1 2-[4-(4-chloro-butyryl)-phenyl]-2-methyl-propionic acid 
• 169280-26-6 2-(4-(1-Oxo-1-cyclopropanyl)-phenyl)-2-methylpropanol 

Relevant articles and documents

FEXOFENADINE POLYMORPHS AND PROCESSES OF PREPARING THE SAME

Anhydrous crystalline fexofenadine hydrochloride Form C, crystalline fexofenadine acetate monohydrate Form D, crystalline fexofenadine acetate dihydrate Form E and crystalline fexofenadine free base monohydrate Form F, processes of preparing the same, pharmaceutical compositions thereof, therapeutic uses thereof and methods of treatment therewith.

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents -C(=O)- or -CH(OH)-; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3 is -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are ta to form a second bond between the carbon R1 and R2 or where R1 represented hydroxy integer 0.