169332-61-0

Basic information

• Product Name: AC-DEVD-AMC
• Synonyms: N-ACETYL-ASP-GLU-VAL-ASP-7-AMINO-4-METHYLCOUMARIN AMC;AC-ASP-MET-GLN-ASP-AMC;AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN;AC-ASP-GLU-VAL-ASP-MCA;AC-ASP-GLU-VAL-ASP-7-AMINO-4-METHYLCOUMARIN;AC-ASP-GLU-VAL-ASP-AMC;AC-ASP-GLU-VAL-ASP-AMC AMMONIUM SALT;AC-DEVD-AMC
• CAS NO: 169332-61-0
• Molecular Formula: C30H37N5O13
• Molecular Weight: 675.64
• Product Categories: peptide;Pepetides
• Mol File: 169332-61-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1200.1 °C at 760 mmHg
• Flash Point: 679.6 °C
• Appearance: white/powder
• Density: 1.423 g/cm³
• Storage Temp.: −20°C
• Solubility: DMSO: 10 mM
• PKA: 4.09±0.10(Predicted)
• CAS DataBase Reference: AC-DEVD-AMC(CAS DataBase Reference)
• NIST Chemistry Reference: AC-DEVD-AMC(169332-61-0)
• EPA Substance Registry System: AC-DEVD-AMC(169332-61-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 169332-61-0(Hazardous Substances Data)

Usage

Uses

N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin has been used as a substrate for caspase-3 assay in human colon cancer cell line and in bone marrow mesenchymal stem cells.

Biochem/physiol Actions

Fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.